Expanded newborn screening: Guiding principles, concerns and relevance
Since its introduction in 1960s, universal newborn screening (NBS) using the heel-prick dried blood spot samples has become an integral part of public health system in developed countries expanded to pre-symptomatic detection of specific inherited metabolic, endocrine and hematologic disorders. In o...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Muller Journal of Medical Sciences and Research |
| Subjects: | |
| Online Access: | http://www.mjmsr.net/article.asp?issn=0975-9727;year=2014;volume=5;issue=1;spage=59;epage=63;aulast=Sindgikar |
| _version_ | 1818206308848893952 |
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| author | Seema Pavaman Sindgikar Rathika Damodar Shenoy |
| author_facet | Seema Pavaman Sindgikar Rathika Damodar Shenoy |
| author_sort | Seema Pavaman Sindgikar |
| collection | DOAJ |
| description | Since its introduction in 1960s, universal newborn screening (NBS) using the heel-prick dried blood spot samples has become an integral part of public health system in developed countries expanded to pre-symptomatic detection of specific inherited metabolic, endocrine and hematologic disorders. In our country, NBS may become relevant with epidemiological shift and increasing access to technology. Current recommendations include a phased introduction of screening for congenital hypothyroidism, congenital adrenal hyperplasia and glucose 6-phosphate dehydrogenase deficiency. In this review, the guiding principles of NBS, some of the individual disorders, the concerns and relevance to our country are discussed. Establishing a pre- and post-screening care and education are of utmost priority before NBS is adapted into health care system. |
| first_indexed | 2024-12-12T04:10:58Z |
| format | Article |
| id | doaj.art-da92fbef6cef4967a0ba1bc1e4b63e12 |
| institution | Directory Open Access Journal |
| issn | 0975-9727 |
| language | English |
| last_indexed | 2024-12-12T04:10:58Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Muller Journal of Medical Sciences and Research |
| spelling | doaj.art-da92fbef6cef4967a0ba1bc1e4b63e122022-12-22T00:38:37ZengWolters Kluwer Medknow PublicationsMuller Journal of Medical Sciences and Research0975-97272014-01-0151596310.4103/0975-9727.128951Expanded newborn screening: Guiding principles, concerns and relevanceSeema Pavaman SindgikarRathika Damodar ShenoySince its introduction in 1960s, universal newborn screening (NBS) using the heel-prick dried blood spot samples has become an integral part of public health system in developed countries expanded to pre-symptomatic detection of specific inherited metabolic, endocrine and hematologic disorders. In our country, NBS may become relevant with epidemiological shift and increasing access to technology. Current recommendations include a phased introduction of screening for congenital hypothyroidism, congenital adrenal hyperplasia and glucose 6-phosphate dehydrogenase deficiency. In this review, the guiding principles of NBS, some of the individual disorders, the concerns and relevance to our country are discussed. Establishing a pre- and post-screening care and education are of utmost priority before NBS is adapted into health care system.http://www.mjmsr.net/article.asp?issn=0975-9727;year=2014;volume=5;issue=1;spage=59;epage=63;aulast=SindgikarCongenital hypothyroidismdried blood spotGuthrie cardphenylketonuriatandem mass spectrometry |
| spellingShingle | Seema Pavaman Sindgikar Rathika Damodar Shenoy Expanded newborn screening: Guiding principles, concerns and relevance Muller Journal of Medical Sciences and Research Congenital hypothyroidism dried blood spot Guthrie card phenylketonuria tandem mass spectrometry |
| title | Expanded newborn screening: Guiding principles, concerns and relevance |
| title_full | Expanded newborn screening: Guiding principles, concerns and relevance |
| title_fullStr | Expanded newborn screening: Guiding principles, concerns and relevance |
| title_full_unstemmed | Expanded newborn screening: Guiding principles, concerns and relevance |
| title_short | Expanded newborn screening: Guiding principles, concerns and relevance |
| title_sort | expanded newborn screening guiding principles concerns and relevance |
| topic | Congenital hypothyroidism dried blood spot Guthrie card phenylketonuria tandem mass spectrometry |
| url | http://www.mjmsr.net/article.asp?issn=0975-9727;year=2014;volume=5;issue=1;spage=59;epage=63;aulast=Sindgikar |
| work_keys_str_mv | AT seemapavamansindgikar expandednewbornscreeningguidingprinciplesconcernsandrelevance AT rathikadamodarshenoy expandednewbornscreeningguidingprinciplesconcernsandrelevance |