Gelatin and lipidoid integrate to create gelasomes to enhance siRNA delivery with low toxicity

RNAi therapeutics possess the potential to cure many uncurable human diseases. For instance, RNAi therapeutics using liposomes showed remarkable survival benefits in patients with liver diseases. However, the extension of liposomes to deliver RNA to cure other ailments has largely been unsuccessful....

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Hlavní autoři: Abilash Gangula, Dhananjay Suresh, Agasthya Suresh Babu, Zhaohui Li, Anandhi Upendran, Raghuraman Kannan
Médium: Článek
Jazyk:English
Vydáno: KeAi Communications Co., Ltd. 2024-10-01
Edice:Bioactive Materials
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2452199X24002202