A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space

While the typical targets of (chemo-)enzymatic cascades are fine chemicals (e.g., pharmaceuticals), a chemoenzymatic cascade, artificial starch anabolic pathway (ASAP), was recently developed to synthesize starch from CO2. The key results and outstanding features of ASAP are discussed here. We envis...

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Main Authors: Shuke Wu, Uwe T. Bornscheuer
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Engineering Microbiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667370321000060
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author Shuke Wu
Uwe T. Bornscheuer
author_facet Shuke Wu
Uwe T. Bornscheuer
author_sort Shuke Wu
collection DOAJ
description While the typical targets of (chemo-)enzymatic cascades are fine chemicals (e.g., pharmaceuticals), a chemoenzymatic cascade, artificial starch anabolic pathway (ASAP), was recently developed to synthesize starch from CO2. The key results and outstanding features of ASAP are discussed here. We envision that ASAP and its microbial counterpart may enable efficient synthesis of food and sequestration of CO2 in a circular manner, thus contributing to a sustainable and hunger-free world and future habitation in space.
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spelling doaj.art-da9a0d98fc67450a9b86dc1de986392a2023-07-04T05:11:20ZengElsevierEngineering Microbiology2667-37032022-03-0121100006A chemoenzymatic cascade with the potential to feed the world and allow humans to live in spaceShuke Wu0Uwe T. Bornscheuer1State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China; Corresponding author.Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry, University Greifswald, D-17487 Greifswald, Germany; Corresponding author.While the typical targets of (chemo-)enzymatic cascades are fine chemicals (e.g., pharmaceuticals), a chemoenzymatic cascade, artificial starch anabolic pathway (ASAP), was recently developed to synthesize starch from CO2. The key results and outstanding features of ASAP are discussed here. We envision that ASAP and its microbial counterpart may enable efficient synthesis of food and sequestration of CO2 in a circular manner, thus contributing to a sustainable and hunger-free world and future habitation in space.http://www.sciencedirect.com/science/article/pii/S2667370321000060Chemoenzymatic cascadeCell-free systemCarbon dioxideArtificial pathway
spellingShingle Shuke Wu
Uwe T. Bornscheuer
A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space
Engineering Microbiology
Chemoenzymatic cascade
Cell-free system
Carbon dioxide
Artificial pathway
title A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space
title_full A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space
title_fullStr A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space
title_full_unstemmed A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space
title_short A chemoenzymatic cascade with the potential to feed the world and allow humans to live in space
title_sort chemoenzymatic cascade with the potential to feed the world and allow humans to live in space
topic Chemoenzymatic cascade
Cell-free system
Carbon dioxide
Artificial pathway
url http://www.sciencedirect.com/science/article/pii/S2667370321000060
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