Impact of C-Terminal Chemistry on Self-Assembled Morphology of Guanosine Containing Nucleopeptides

Impact of C-Terminal Chemistry on Self-Assembled Morphology of Guanosine Containing Nucleopeptides

Herein, we report the design and characterization of guanosine-containing self-assembling nucleopeptides that form nanosheets and nanofibers. Through spectroscopy and microscopy analysis, we propose that the peptide component of the nucleopeptide drives the assembly into β-sheet structures with hydr...

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Bibliographic Details
Main Authors: Katherine Boback, Katherine Bacchi, Sarah O’Neill, Samantha Brown, Jovelt Dorsainvil, Jillian E. Smith-Carpenter
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
nucleopeptide
self-assembly
guanosine
G-quartet
Online Access:https://www.mdpi.com/1420-3049/25/23/5493

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