Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa
Background: Carvacrol is the main phenolic compound of Satureja and thyme. Carvacrol has antibacterial, antifungal, anti-inflammatory, and anti-cancer properties.Objectives: The aim of this study is determine the peptide-modified carvacrol’s antibacterial effects against Staphylococcus epidermidis a...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sadra Danesh Negar
2022-08-01
|
| Series: | Novelty in Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.nclinmed.com/article_154681_2e6301ce3e1e8bb78faf0cc00d4d2e90.pdf |
| _version_ | 1797328345263767552 |
|---|---|
| author | Mona Ghod Elahi Malak Hekmati Davoud Esmaeili Parisa Ziarati Mohamad Yousefi |
| author_facet | Mona Ghod Elahi Malak Hekmati Davoud Esmaeili Parisa Ziarati Mohamad Yousefi |
| author_sort | Mona Ghod Elahi |
| collection | DOAJ |
| description | Background: Carvacrol is the main phenolic compound of Satureja and thyme. Carvacrol has antibacterial, antifungal, anti-inflammatory, and anti-cancer properties.Objectives: The aim of this study is determine the peptide-modified carvacrol’s antibacterial effects against Staphylococcus epidermidis and Pseudomonas aeruginosa.Methods: The peptide-modified carvacrol’s antibacterial activity against Staphylococcus epidermidis and Pseudomonas aeruginosa was investigated by disk diffusion and MIC method.Results: The effects of modified carvacrol by the disk diffusion method had growth inhibition diameters of 25mm and 20mm against Staphylococcus epidermidis and Pseudomonas aeruginosa, respectively. Also, MIC against Staphylococcus epidermidis and Pseudomonas aeruginosa was 1µg/ml and 0.51µg/ml, respectively.Conclusion: The peptide-modified carvacrol has some antibacterial effects. |
| first_indexed | 2024-03-08T06:50:29Z |
| format | Article |
| id | doaj.art-da9f1046d0504e39b21ca6bc3f8e9f34 |
| institution | Directory Open Access Journal |
| issn | 2783-4492 |
| language | English |
| last_indexed | 2024-03-08T06:50:29Z |
| publishDate | 2022-08-01 |
| publisher | Sadra Danesh Negar |
| record_format | Article |
| series | Novelty in Clinical Medicine |
| spelling | doaj.art-da9f1046d0504e39b21ca6bc3f8e9f342024-02-03T07:07:36ZengSadra Danesh NegarNovelty in Clinical Medicine2783-44922022-08-011419219610.22034/ncm.2022.350997.1051154681Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosaMona Ghod Elahi0Malak Hekmati1Davoud Esmaeili2Parisa Ziarati3Mohamad Yousefi4Department of Organic Chemistry, Faculty of Pharmaceutical Chemistry, Tehran Medical Sciences, Islamic Azad University, Tehran, IranDepartment of Organic Chemistry, Faculty of Pharmaceutical Chemistry, Tehran Medical Sciences, Islamic Azad University, Tehran, IranDepartment of Microbiology and Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IranDepartment of Medicinal Chemistry, Pharmacy Faculty, Tehran Medical Sciences, Islamic Azad University, Tehran, IranDepartment of Chemistry, Faculty of Pharmaceutical Chemistry, Tehran Medical Sciences, Islamic Azad University, Tehran, IranBackground: Carvacrol is the main phenolic compound of Satureja and thyme. Carvacrol has antibacterial, antifungal, anti-inflammatory, and anti-cancer properties.Objectives: The aim of this study is determine the peptide-modified carvacrol’s antibacterial effects against Staphylococcus epidermidis and Pseudomonas aeruginosa.Methods: The peptide-modified carvacrol’s antibacterial activity against Staphylococcus epidermidis and Pseudomonas aeruginosa was investigated by disk diffusion and MIC method.Results: The effects of modified carvacrol by the disk diffusion method had growth inhibition diameters of 25mm and 20mm against Staphylococcus epidermidis and Pseudomonas aeruginosa, respectively. Also, MIC against Staphylococcus epidermidis and Pseudomonas aeruginosa was 1µg/ml and 0.51µg/ml, respectively.Conclusion: The peptide-modified carvacrol has some antibacterial effects.https://www.nclinmed.com/article_154681_2e6301ce3e1e8bb78faf0cc00d4d2e90.pdfantibacterialmodified carvacrolstaphylococcus epidermidispseudomonas aeruginosa |
| spellingShingle | Mona Ghod Elahi Malak Hekmati Davoud Esmaeili Parisa Ziarati Mohamad Yousefi Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa Novelty in Clinical Medicine antibacterial modified carvacrol staphylococcus epidermidis pseudomonas aeruginosa |
| title | Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa |
| title_full | Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa |
| title_fullStr | Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa |
| title_full_unstemmed | Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa |
| title_short | Antibacterial Activity of Modified Carvacrol against Staphylococcus epidermidis and Pseudomonas aeruginosa |
| title_sort | antibacterial activity of modified carvacrol against staphylococcus epidermidis and pseudomonas aeruginosa |
| topic | antibacterial modified carvacrol staphylococcus epidermidis pseudomonas aeruginosa |
| url | https://www.nclinmed.com/article_154681_2e6301ce3e1e8bb78faf0cc00d4d2e90.pdf |
| work_keys_str_mv | AT monaghodelahi antibacterialactivityofmodifiedcarvacrolagainststaphylococcusepidermidisandpseudomonasaeruginosa AT malakhekmati antibacterialactivityofmodifiedcarvacrolagainststaphylococcusepidermidisandpseudomonasaeruginosa AT davoudesmaeili antibacterialactivityofmodifiedcarvacrolagainststaphylococcusepidermidisandpseudomonasaeruginosa AT parisaziarati antibacterialactivityofmodifiedcarvacrolagainststaphylococcusepidermidisandpseudomonasaeruginosa AT mohamadyousefi antibacterialactivityofmodifiedcarvacrolagainststaphylococcusepidermidisandpseudomonasaeruginosa |