Immunolabeling-compatible PEGASOS tissue clearing for high-resolution whole mouse brain imaging

Immunolabeling-compatible PEGASOS tissue clearing for high-resolution whole mouse brain imaging

Novel brain clearing methods revolutionize imaging by increasing visualization throughout the brain at high resolution. However, combining the standard tool of immunostaining targets of interest with clearing methods has lagged behind. We integrate whole-mount immunostaining with PEGASOS tissue clea...

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Bibliographic Details
Main Authors:	Pan Gao, Matthew Rivera, Xiaoxiao Lin, Todd C. Holmes, Hu Zhao, Xiangmin Xu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Series:	Frontiers in Neural Circuits
Subjects:	tissue clearing whole-mount immunostaining circuit tracing Alzheimer’s disease Light-Sheet
Online Access:	https://www.frontiersin.org/articles/10.3389/fncir.2024.1345692/full

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