Development of an <it>in vitro </it>cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity

<p>Abstract</p> <p>Through the use of transient expression assays and directed genetics, the vaccinia virus (VV) I7L gene product has been implicated as the major maturational proteinase required for viral core protein cleavage to occur during virion assembly. To confirm this hypot...

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Bibliographic Details
Main Authors: Hruby Dennis E, Byrd Chelsea M
Format: Article
Language:English
Published: BMC 2005-08-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/2/1/63