Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material

A Burch–Schneider (BS) cage is a reinforcement device used in total hip arthroplasty (THA) revision surgeries to bridge areas of acetabular loss. There have been a variety of BS cages in the market, which are made of solid metal. However, significant differences in structural configuration and mecha...

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Main Authors: Manman Xu, Yan Zhang, Shuting Wang, Guozhang Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.819005/full
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author Manman Xu
Manman Xu
Manman Xu
Yan Zhang
Yan Zhang
Shuting Wang
Guozhang Jiang
Guozhang Jiang
author_facet Manman Xu
Manman Xu
Manman Xu
Yan Zhang
Yan Zhang
Shuting Wang
Guozhang Jiang
Guozhang Jiang
author_sort Manman Xu
collection DOAJ
description A Burch–Schneider (BS) cage is a reinforcement device used in total hip arthroplasty (THA) revision surgeries to bridge areas of acetabular loss. There have been a variety of BS cages in the market, which are made of solid metal. However, significant differences in structural configuration and mechanical behavior between bone and metal implants cause bone resorption and interface loosening, and hence lead to failure of the implant in the long term. To address this issue, an optimal design framework for a cellular BS cage was investigated in this study by genetic algorithm and topology optimization, inspired by porous human bone with variable holes. In this optimization, a BS cage is constructed with functionally graded lattice material which gradually evolves to achieve better mechanical behavior by natural selection and natural genetics. Clinical constraints that allow adequate bone ingrowth and manufacturing constraint that ensures the realization of the optimized implant are considered simultaneously. A homogenization method is introduced to calculate effective mechanical properties of octet-truss lattice material in a given range of relative density. At last, comparison of the optimum lattice BS cage with a fully solid cage and a lattice cage with identical element density indicates the validity of the optimization design strategy proposed in this article.
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spelling doaj.art-daa4bc25aa43471da9f40f64bcb5d7aa2022-12-22T04:10:06ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-01-011010.3389/fbioe.2022.819005819005Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice MaterialManman Xu0Manman Xu1Manman Xu2Yan Zhang3Yan Zhang4Shuting Wang5Guozhang Jiang6Guozhang Jiang7Key Laboratory of Metallurgical Equipment and Control Technology of Ministry of Education, Wuhan University of Science and Technology, Wuhan, ChinaHubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering, Wuhan University of Science and Technology, Wuhan, ChinaResearch Center for Biomimetic Robot and Intelligent Measurement and Control, Wuhan University of Science and Technology, Wuhan, ChinaKey Laboratory of Metallurgical Equipment and Control Technology of Ministry of Education, Wuhan University of Science and Technology, Wuhan, ChinaHubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering, Wuhan University of Science and Technology, Wuhan, ChinaSchool of Mechanical Science and Engineering, Huazhong University of Science and Technology, Wuhan, ChinaKey Laboratory of Metallurgical Equipment and Control Technology of Ministry of Education, Wuhan University of Science and Technology, Wuhan, ChinaHubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering, Wuhan University of Science and Technology, Wuhan, ChinaA Burch–Schneider (BS) cage is a reinforcement device used in total hip arthroplasty (THA) revision surgeries to bridge areas of acetabular loss. There have been a variety of BS cages in the market, which are made of solid metal. However, significant differences in structural configuration and mechanical behavior between bone and metal implants cause bone resorption and interface loosening, and hence lead to failure of the implant in the long term. To address this issue, an optimal design framework for a cellular BS cage was investigated in this study by genetic algorithm and topology optimization, inspired by porous human bone with variable holes. In this optimization, a BS cage is constructed with functionally graded lattice material which gradually evolves to achieve better mechanical behavior by natural selection and natural genetics. Clinical constraints that allow adequate bone ingrowth and manufacturing constraint that ensures the realization of the optimized implant are considered simultaneously. A homogenization method is introduced to calculate effective mechanical properties of octet-truss lattice material in a given range of relative density. At last, comparison of the optimum lattice BS cage with a fully solid cage and a lattice cage with identical element density indicates the validity of the optimization design strategy proposed in this article.https://www.frontiersin.org/articles/10.3389/fbioe.2022.819005/fullgenetic algorithmbioengineeringlattice materialstructural optimizationBurch-Schneider cage
spellingShingle Manman Xu
Manman Xu
Manman Xu
Yan Zhang
Yan Zhang
Shuting Wang
Guozhang Jiang
Guozhang Jiang
Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material
Frontiers in Bioengineering and Biotechnology
genetic algorithm
bioengineering
lattice material
structural optimization
Burch-Schneider cage
title Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material
title_full Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material
title_fullStr Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material
title_full_unstemmed Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material
title_short Genetic-Based Optimization of 3D Burch–Schneider Cage With Functionally Graded Lattice Material
title_sort genetic based optimization of 3d burch schneider cage with functionally graded lattice material
topic genetic algorithm
bioengineering
lattice material
structural optimization
Burch-Schneider cage
url https://www.frontiersin.org/articles/10.3389/fbioe.2022.819005/full
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