Prevalence of anxiety and depression in South Asia during COVID-19: A systematic review and meta-analysis

Introduction: The COVID-19 pandemic has impacted biopsychosocial health and wellbeing globally. Pre-pandemic studies suggest a high prevalence of common mental disorders, including anxiety and depression in South Asian countries, which may aggravate during this pandemic. This systematic meta-analyti...

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Main Authors: Md Mahbub Hossain, Mariya Rahman, Nusrat Fahmida Trisha, Samia Tasnim, Tasmiah Nuzhath, Nishat Tasnim Hasan, Heather Clark, Arindam Das, E. Lisako J. McKyer, Helal Uddin Ahmed, Ping Ma
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021007805
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author Md Mahbub Hossain
Mariya Rahman
Nusrat Fahmida Trisha
Samia Tasnim
Tasmiah Nuzhath
Nishat Tasnim Hasan
Heather Clark
Arindam Das
E. Lisako J. McKyer
Helal Uddin Ahmed
Ping Ma
author_facet Md Mahbub Hossain
Mariya Rahman
Nusrat Fahmida Trisha
Samia Tasnim
Tasmiah Nuzhath
Nishat Tasnim Hasan
Heather Clark
Arindam Das
E. Lisako J. McKyer
Helal Uddin Ahmed
Ping Ma
author_sort Md Mahbub Hossain
collection DOAJ
description Introduction: The COVID-19 pandemic has impacted biopsychosocial health and wellbeing globally. Pre-pandemic studies suggest a high prevalence of common mental disorders, including anxiety and depression in South Asian countries, which may aggravate during this pandemic. This systematic meta-analytic review was conducted to estimate the pooled prevalence of anxiety and depression in South Asian countries during the COVID-19 pandemic. Method: We systematically searched for cross-sectional studies on eight major bibliographic databases and additional sources up to October 12, 2020, that reported the prevalence of anxiety or depression in any of the eight South Asian countries. A random-effects model was used to calculate the pooled proportion of anxiety and depression. Results: A total of 35 studies representing 41,402 participants were included in this review. The pooled prevalence of anxiety in 31 studies with a pooled sample of 28,877 was 41.3% (95% confidence interval [CI]: 34.7–48.1, I2 = 99.18%). Moreover, the pooled prevalence of depression was 34.1% (95% CI: 28.9–39.4, I2 = 99%) among 37,437 participants in 28 studies. Among the South Asian countries, India had a higher number of studies, whereas Bangladesh and Pakistan had a higher pooled prevalence of anxiety and depression. No studies were identified from Afghanistan, Bhutan, and Maldives. Studies in this review had high heterogeneity, high publication bias confirmed by Egger's test, and varying prevalence rates across sub-groups. Conclusion: South Asian countries have high prevalence rates of anxiety and depression, suggesting a heavy psychosocial burden during this pandemic. Clinical and public mental health interventions should be prioritized alongside improving the social determinants of mental health in these countries. Lastly, a low number of studies with high heterogeneity requires further research exploring the psychosocial epidemiology during COVID-19, which may inform better mental health policymaking and practice in South Asia.
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spelling doaj.art-daacd9201a9c4e9d82802f7992920aa22022-12-21T22:11:11ZengElsevierHeliyon2405-84402021-04-0174e06677Prevalence of anxiety and depression in South Asia during COVID-19: A systematic review and meta-analysisMd Mahbub Hossain0Mariya Rahman1Nusrat Fahmida Trisha2Samia Tasnim3Tasmiah Nuzhath4Nishat Tasnim Hasan5Heather Clark6Arindam Das7E. Lisako J. McKyer8Helal Uddin Ahmed9Ping Ma10School of Public Health, Texas A&M University, College Station, TX 77843, United States; Corresponding author.School of Public Health, Texas A&M University, College Station, TX 77843, United StatesSchool of Public Health, Texas A&M University, College Station, TX 77843, United StatesSchool of Public Health, Texas A&M University, College Station, TX 77843, United StatesSchool of Public Health, Texas A&M University, College Station, TX 77843, United StatesSchool of Public Health, Texas A&M University, College Station, TX 77843, United StatesSchool of Public Health, Texas A&M University, College Station, TX 77843, United StatesThe IIHMR University, Jaipur, Rajasthan 302029, IndiaSchool of Public Health, Texas A&M University, College Station, TX 77843, United StatesNational Institute of Mental Health (NIMH), Sher-E-Bangla Nagar, Dhaka 1207, BangladeshSchool of Public Health, Texas A&M University, College Station, TX 77843, United StatesIntroduction: The COVID-19 pandemic has impacted biopsychosocial health and wellbeing globally. Pre-pandemic studies suggest a high prevalence of common mental disorders, including anxiety and depression in South Asian countries, which may aggravate during this pandemic. This systematic meta-analytic review was conducted to estimate the pooled prevalence of anxiety and depression in South Asian countries during the COVID-19 pandemic. Method: We systematically searched for cross-sectional studies on eight major bibliographic databases and additional sources up to October 12, 2020, that reported the prevalence of anxiety or depression in any of the eight South Asian countries. A random-effects model was used to calculate the pooled proportion of anxiety and depression. Results: A total of 35 studies representing 41,402 participants were included in this review. The pooled prevalence of anxiety in 31 studies with a pooled sample of 28,877 was 41.3% (95% confidence interval [CI]: 34.7–48.1, I2 = 99.18%). Moreover, the pooled prevalence of depression was 34.1% (95% CI: 28.9–39.4, I2 = 99%) among 37,437 participants in 28 studies. Among the South Asian countries, India had a higher number of studies, whereas Bangladesh and Pakistan had a higher pooled prevalence of anxiety and depression. No studies were identified from Afghanistan, Bhutan, and Maldives. Studies in this review had high heterogeneity, high publication bias confirmed by Egger's test, and varying prevalence rates across sub-groups. Conclusion: South Asian countries have high prevalence rates of anxiety and depression, suggesting a heavy psychosocial burden during this pandemic. Clinical and public mental health interventions should be prioritized alongside improving the social determinants of mental health in these countries. Lastly, a low number of studies with high heterogeneity requires further research exploring the psychosocial epidemiology during COVID-19, which may inform better mental health policymaking and practice in South Asia.http://www.sciencedirect.com/science/article/pii/S2405844021007805COVID-19Mental healthAnxietyDepressionSouth AsiaAfghanistan
spellingShingle Md Mahbub Hossain
Mariya Rahman
Nusrat Fahmida Trisha
Samia Tasnim
Tasmiah Nuzhath
Nishat Tasnim Hasan
Heather Clark
Arindam Das
E. Lisako J. McKyer
Helal Uddin Ahmed
Ping Ma
Prevalence of anxiety and depression in South Asia during COVID-19: A systematic review and meta-analysis
Heliyon
COVID-19
Mental health
Anxiety
Depression
South Asia
Afghanistan
title Prevalence of anxiety and depression in South Asia during COVID-19: A systematic review and meta-analysis
title_full Prevalence of anxiety and depression in South Asia during COVID-19: A systematic review and meta-analysis
title_fullStr Prevalence of anxiety and depression in South Asia during COVID-19: A systematic review and meta-analysis
title_full_unstemmed Prevalence of anxiety and depression in South Asia during COVID-19: A systematic review and meta-analysis
title_short Prevalence of anxiety and depression in South Asia during COVID-19: A systematic review and meta-analysis
title_sort prevalence of anxiety and depression in south asia during covid 19 a systematic review and meta analysis
topic COVID-19
Mental health
Anxiety
Depression
South Asia
Afghanistan
url http://www.sciencedirect.com/science/article/pii/S2405844021007805
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