Highly tumorigenic hepatocellular carcinoma cell line with cancer stem cell-like properties.

Highly tumorigenic hepatocellular carcinoma cell line with cancer stem cell-like properties.

There are limited numbers of models to study hepatocellular carcinoma (HCC) in vivo in immunocompetent hosts. In an effort to develop a cell line with improved tumorigenicity, we derived a new cell line from Hepa1-6 cells through an in vivo passage in C57BL/6 mice. The resulting Dt81Hepa1-6 cell lin...

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Bibliographic Details
Main Authors: Benoit Lacoste, Valérie-Ann Raymond, Shamir Cassim, Pascal Lapierre, Marc Bilodeau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5289561?pdf=render

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