Dimethyl fumarate protects pancreatic islet cells and non-endocrine tissue in L-arginine-induced chronic pancreatitis.

Chronic pancreatitis (CP) is a progressive disorder resulting in the destruction and fibrosis of the pancreatic parenchyma which ultimately leads to impairment of the endocrine and exocrine functions. Dimethyl Fumarate (DMF) was recently approved by FDA for treatment of patients with multiple sclero...

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Bibliographic Details
Main Authors: Lourdes Robles, Nosratola D Vaziri, Shiri Li, Yuichi Masuda, Chie Takasu, Mizuki Takasu, Kelly Vo, Seyed H Farzaneh, Michael J Stamos, Hirohito Ichii
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4157838?pdf=render

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