Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital
The aim of the present study was to identify the incidence of sepsis among neonates admitted at Beni-Suef University Hospital during the period of the study, to identify different organisms responsible for sepsis and the serum level of CD14 (presepsin) was investigated as a biomarker of sepsis. All...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Beni-Suef University, Faculty of Medicine
2022-01-01
|
| Series: | Egyptian Journal of Medical Research |
| Subjects: | |
| Online Access: | https://ejmr.journals.ekb.eg/article_221866_e141b9626119d5e459adf1c3d6765a51.pdf |
| _version_ | 1797894020148494336 |
|---|---|
| author | Aya Mahmoud Nermin Ibrahim Sameh Fahmy Mervat Tohamy |
| author_facet | Aya Mahmoud Nermin Ibrahim Sameh Fahmy Mervat Tohamy |
| author_sort | Aya Mahmoud |
| collection | DOAJ |
| description | The aim of the present study was to identify the incidence of sepsis among neonates admitted at Beni-Suef University Hospital during the period of the study, to identify different organisms responsible for sepsis and the serum level of CD14 (presepsin) was investigated as a biomarker of sepsis. All neonates suspected with sepsis during the time of the study admitted in neonatal intensive care unit at Beni-Suef University Hospital were screened for sepsis by blood culture and presepsin levels were investigated. The incidence of sepsis was 32.4%. Presepsin marker had a significant role in prediction of presence of sepsis, at a cut off value of 2300 or more of presepsin, it can predict the presence of sepsis with sensitivity of (94.29%), specificity of (88.6%), positive predictive value (89.2%) and negative predictive value (93.9%) |
| first_indexed | 2024-04-10T07:02:10Z |
| format | Article |
| id | doaj.art-dab0ac680de74e88bbc66405d71eaca7 |
| institution | Directory Open Access Journal |
| issn | 2682-4396 2682-440X |
| language | English |
| last_indexed | 2024-04-10T07:02:10Z |
| publishDate | 2022-01-01 |
| publisher | Beni-Suef University, Faculty of Medicine |
| record_format | Article |
| series | Egyptian Journal of Medical Research |
| spelling | doaj.art-dab0ac680de74e88bbc66405d71eaca72023-02-27T17:41:44ZengBeni-Suef University, Faculty of MedicineEgyptian Journal of Medical Research2682-43962682-440X2022-01-013121022110.21608/ejmr.2022.221866221866Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University HospitalAya Mahmoud0Nermin Ibrahim1Sameh Fahmy2Mervat Tohamy3Medical Microbiology and Immunology department, Faculty of Medicine, Beni-Suef University, EgyptMedical Microbiology and Immunology department, Faculty of Medicine, Beni-Suef University, EgyptPediatrics department, Faculty of Medicine, Beni-Suef University, EgyptMedical Microbiology and Immunology department, Faculty of Medicine, Beni-Suef University, EgyptThe aim of the present study was to identify the incidence of sepsis among neonates admitted at Beni-Suef University Hospital during the period of the study, to identify different organisms responsible for sepsis and the serum level of CD14 (presepsin) was investigated as a biomarker of sepsis. All neonates suspected with sepsis during the time of the study admitted in neonatal intensive care unit at Beni-Suef University Hospital were screened for sepsis by blood culture and presepsin levels were investigated. The incidence of sepsis was 32.4%. Presepsin marker had a significant role in prediction of presence of sepsis, at a cut off value of 2300 or more of presepsin, it can predict the presence of sepsis with sensitivity of (94.29%), specificity of (88.6%), positive predictive value (89.2%) and negative predictive value (93.9%)https://ejmr.journals.ekb.eg/article_221866_e141b9626119d5e459adf1c3d6765a51.pdfneonatal sepsiscd14presepsin |
| spellingShingle | Aya Mahmoud Nermin Ibrahim Sameh Fahmy Mervat Tohamy Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital Egyptian Journal of Medical Research neonatal sepsis cd14 presepsin |
| title | Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital |
| title_full | Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital |
| title_fullStr | Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital |
| title_full_unstemmed | Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital |
| title_short | Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital |
| title_sort | evaluation of serum levels of cd14 in neonatal sepsis and its correlation with type of infection in beni suef university hospital |
| topic | neonatal sepsis cd14 presepsin |
| url | https://ejmr.journals.ekb.eg/article_221866_e141b9626119d5e459adf1c3d6765a51.pdf |
| work_keys_str_mv | AT ayamahmoud evaluationofserumlevelsofcd14inneonatalsepsisanditscorrelationwithtypeofinfectioninbenisuefuniversityhospital AT nerminibrahim evaluationofserumlevelsofcd14inneonatalsepsisanditscorrelationwithtypeofinfectioninbenisuefuniversityhospital AT samehfahmy evaluationofserumlevelsofcd14inneonatalsepsisanditscorrelationwithtypeofinfectioninbenisuefuniversityhospital AT mervattohamy evaluationofserumlevelsofcd14inneonatalsepsisanditscorrelationwithtypeofinfectioninbenisuefuniversityhospital |