Nonhistone Proteins HMGB1 and HMGB2 Differentially Modulate the Response of Human Embryonic Stem Cells and the Progenitor Cells to the Anticancer Drug Etoposide

Nonhistone Proteins HMGB1 and HMGB2 Differentially Modulate the Response of Human Embryonic Stem Cells and the Progenitor Cells to the Anticancer Drug Etoposide

HMGB1 and HMGB2 proteins are abundantly expressed in human embryonic stem cells<br />(hESCs) and hESC-derived progenitor cells (neuroectodermal cells, hNECs), though their functional<br />roles in pluripotency and the mechanisms underlying their dierentiation in response to the anticance...

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Bibliographic Details
Main Authors: Alireza Jian Bagherpoor, Martin Kučírek, Radek Fedr, Soodabeh Abbasi Sani, Michal Štros
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomolecules
Subjects:
HMGB1 and HMGB2
human embryonic stem cells
neuroectodermal cells
apoptosis
telomerase
etoposide
Online Access:https://www.mdpi.com/2218-273X/10/10/1450

Internet

https://www.mdpi.com/2218-273X/10/10/1450

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