Leishmania braziliensis: partial control of experimental infection by interleukin-12 p40 deficient mice

Resistance to infection by Leishmania major has been associated with the development of a Th1 type response that is dependent on the presence of interleukin 12 (IL-12). In this work the involvement of this cytokine in the response to infection by L. braziliensis, a less virulent species in the mouse...

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Bibliographic Details
Main Authors: Sebastião Martins de Souza-Neto, Cláudia Martins Carneiro, Leda Quercia Vieira, Luís Carlos Crocco Afonso
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2004-05-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300009