Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation
BackgroundIndirect cardiomyocyte damage-related hyperinflammatory response is one of the key mechanisms in COVID-19-induced fulminant myocarditis. In addition to the clinical benefit of using cytokines absorption hemofiltration, the effectiveness of instituting veno-arterial extracorporeal membrane...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.946547/full |
| _version_ | 1828780230441959424 |
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| author | Phuc H. Phan Dung T. Nguyen Nam H. Dao Ha T. T. Nguyen An V. Vu Son T. Hoang Lam V. Nguyen Tung V. Cao Dien M. Tran |
| author_facet | Phuc H. Phan Dung T. Nguyen Nam H. Dao Ha T. T. Nguyen An V. Vu Son T. Hoang Lam V. Nguyen Tung V. Cao Dien M. Tran |
| author_sort | Phuc H. Phan |
| collection | DOAJ |
| description | BackgroundIndirect cardiomyocyte damage-related hyperinflammatory response is one of the key mechanisms in COVID-19-induced fulminant myocarditis. In addition to the clinical benefit of using cytokines absorption hemofiltration, the effectiveness of instituting veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support for cardiac compromise has been reported. However, current literature enunciates a paucity of available data on the effectiveness of these novel modalities.Case PresentationWe reported a 9-year-old boy with recurrent COVID-19 infection-causing fulminant myocarditis, who was treated successfully by using novel modalities of oXiris® hemofilter continuous venovenous hemofiltration (CVVH) and VA-ECMO. The patient made a full recovery without any sequelae.ConclusionWe conclude that the novel highly-absorptive hemofilter CVVH and VA-ECMO may be effective treatment modalities in managing SARS-CoV-2-induced fulminant myocarditis. Our report highlights the need for further well-designed investigations to confirm this extrapolation. |
| first_indexed | 2024-12-11T17:14:58Z |
| format | Article |
| id | doaj.art-dab9000487ba4d498b45cc10a2d7781d |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-11T17:14:58Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-dab9000487ba4d498b45cc10a2d7781d2022-12-22T00:57:24ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-07-011010.3389/fped.2022.946547946547Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane OxygenationPhuc H. Phan0Dung T. Nguyen1Nam H. Dao2Ha T. T. Nguyen3An V. Vu4Son T. Hoang5Lam V. Nguyen6Tung V. Cao7Dien M. Tran8Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, VietnamPediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, VietnamPediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, VietnamPediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, VietnamPediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, VietnamCardiovascular Center, Vietnam National Children's Hospital, Hanoi, VietnamPediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, VietnamPediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, VietnamPediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, VietnamBackgroundIndirect cardiomyocyte damage-related hyperinflammatory response is one of the key mechanisms in COVID-19-induced fulminant myocarditis. In addition to the clinical benefit of using cytokines absorption hemofiltration, the effectiveness of instituting veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support for cardiac compromise has been reported. However, current literature enunciates a paucity of available data on the effectiveness of these novel modalities.Case PresentationWe reported a 9-year-old boy with recurrent COVID-19 infection-causing fulminant myocarditis, who was treated successfully by using novel modalities of oXiris® hemofilter continuous venovenous hemofiltration (CVVH) and VA-ECMO. The patient made a full recovery without any sequelae.ConclusionWe conclude that the novel highly-absorptive hemofilter CVVH and VA-ECMO may be effective treatment modalities in managing SARS-CoV-2-induced fulminant myocarditis. Our report highlights the need for further well-designed investigations to confirm this extrapolation.https://www.frontiersin.org/articles/10.3389/fped.2022.946547/fullCOVID-19fulminant myocarditisoXiris® hemofilterECMOcase report |
| spellingShingle | Phuc H. Phan Dung T. Nguyen Nam H. Dao Ha T. T. Nguyen An V. Vu Son T. Hoang Lam V. Nguyen Tung V. Cao Dien M. Tran Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation Frontiers in Pediatrics COVID-19 fulminant myocarditis oXiris® hemofilter ECMO case report |
| title | Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation |
| title_full | Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation |
| title_fullStr | Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation |
| title_full_unstemmed | Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation |
| title_short | Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation |
| title_sort | case report successful treatment of a child with covid 19 reinfection induced fulminant myocarditis by cytokine adsorbing oxiris r hemofilter continuous veno venous hemofiltration and extracorporeal membrane oxygenation |
| topic | COVID-19 fulminant myocarditis oXiris® hemofilter ECMO case report |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.946547/full |
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