Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent
Fibrosing mediastinitis (FM) is a rare, potentially progressive disease resulting from an idiosyncratic immune response to a variety of stimuli that lead to fibrous infiltration of the mediastinum and possible narrowing of the bronchovascular structures. We report an unusual case of FM in a pediatri...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | JACC: Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266608492300517X |
| _version_ | 1797390446519910400 |
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| author | Madhusudan Ganigara, MD John J. Flores, MD Jeremy Slivnick, MD Luis Landeras, MD Narutoshi Hibino, MD, PhD Barbara Hendrickson, MD Aliya Husain, MD Luca Vricella, MD Michael G. Earing, MD |
| author_facet | Madhusudan Ganigara, MD John J. Flores, MD Jeremy Slivnick, MD Luis Landeras, MD Narutoshi Hibino, MD, PhD Barbara Hendrickson, MD Aliya Husain, MD Luca Vricella, MD Michael G. Earing, MD |
| author_sort | Madhusudan Ganigara, MD |
| collection | DOAJ |
| description | Fibrosing mediastinitis (FM) is a rare, potentially progressive disease resulting from an idiosyncratic immune response to a variety of stimuli that lead to fibrous infiltration of the mediastinum and possible narrowing of the bronchovascular structures. We report an unusual case of FM in a pediatric patient presenting as myopericarditis and progressing to pericardial thickening and encasement of the mediastinal vascular structures needing surgical intervention. Imaging, including transthoracic echocardiography, cardiac computed tomography, and cardiac magnetic resonance played a crucial role in the diagnosis, assessment, and follow-up. Contrast-enhanced computed tomography can be especially helpful to demonstrate potential findings associated with FM. |
| first_indexed | 2024-03-08T23:10:53Z |
| format | Article |
| id | doaj.art-dab907ccc3cd4fa5baa513c7022fae6b |
| institution | Directory Open Access Journal |
| issn | 2666-0849 |
| language | English |
| last_indexed | 2024-03-08T23:10:53Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JACC: Case Reports |
| spelling | doaj.art-dab907ccc3cd4fa5baa513c7022fae6b2023-12-15T07:25:57ZengElsevierJACC: Case Reports2666-08492024-01-01292102161Fibrosing Mediastinitis Caused by Histoplasmosis in an AdolescentMadhusudan Ganigara, MD0John J. Flores, MD1Jeremy Slivnick, MD2Luis Landeras, MD3Narutoshi Hibino, MD, PhD4Barbara Hendrickson, MD5Aliya Husain, MD6Luca Vricella, MD7Michael G. Earing, MD8Division of Cardiology, Department of Pediatrics, The University of Chicago, Chicago, Illinois, USA; Address for correspondence: Dr Madhusudan Ganigara, The University of Chicago and Biological Sciences, 5841 S Maryland Avenue, Chicago, Illinois 60637, USA.Division of Infectious Diseases, Department of Pediatric and Adult Medicine, The University of Chicago, Chicago, Illinois, USADivision of Cardiology, Department of Medicine, The University of Chicago, Chicago, Illinois, USADivision of Radiology, The University of Chicago, Chicago, Illinois, USADivision of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, Illinois, USADivision of Infectious Diseases, Department of Pediatric and Adult Medicine, The University of Chicago, Chicago, Illinois, USADivision of Pathology, The University of Chicago, Chicago, Illinois, USADivision of Cardiac Surgery, Department of Surgery, The University of Chicago, Chicago, Illinois, USADivision of Cardiology, Department of Pediatrics, The University of Chicago, Chicago, Illinois, USA; Division of Cardiology, Department of Medicine, The University of Chicago, Chicago, Illinois, USAFibrosing mediastinitis (FM) is a rare, potentially progressive disease resulting from an idiosyncratic immune response to a variety of stimuli that lead to fibrous infiltration of the mediastinum and possible narrowing of the bronchovascular structures. We report an unusual case of FM in a pediatric patient presenting as myopericarditis and progressing to pericardial thickening and encasement of the mediastinal vascular structures needing surgical intervention. Imaging, including transthoracic echocardiography, cardiac computed tomography, and cardiac magnetic resonance played a crucial role in the diagnosis, assessment, and follow-up. Contrast-enhanced computed tomography can be especially helpful to demonstrate potential findings associated with FM.http://www.sciencedirect.com/science/article/pii/S266608492300517Xfibrosing mediastinitismyopericarditispediatrics |
| spellingShingle | Madhusudan Ganigara, MD John J. Flores, MD Jeremy Slivnick, MD Luis Landeras, MD Narutoshi Hibino, MD, PhD Barbara Hendrickson, MD Aliya Husain, MD Luca Vricella, MD Michael G. Earing, MD Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent JACC: Case Reports fibrosing mediastinitis myopericarditis pediatrics |
| title | Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent |
| title_full | Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent |
| title_fullStr | Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent |
| title_full_unstemmed | Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent |
| title_short | Fibrosing Mediastinitis Caused by Histoplasmosis in an Adolescent |
| title_sort | fibrosing mediastinitis caused by histoplasmosis in an adolescent |
| topic | fibrosing mediastinitis myopericarditis pediatrics |
| url | http://www.sciencedirect.com/science/article/pii/S266608492300517X |
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