LncRNA SNHG12 promotes cell proliferation and inhibits apoptosis of granulosa cells in polycystic ovarian syndrome by sponging miR-129 and miR-125b

LncRNA SNHG12 promotes cell proliferation and inhibits apoptosis of granulosa cells in polycystic ovarian syndrome by sponging miR-129 and miR-125b

Abstract Background Polycystic ovarian syndrome (PCOS) is the most common endocrine disease in women of childbearing age which is often associated with abnormal proliferation or apoptosis of granulosa cells (GCs). Studies proved that long non-coding RNA SNHG12 (lncRNA SNHG12) is significantly increa...

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Bibliographic Details
Main Authors: Feilan Xuan, Ruiying Jin, Weimei Zhou, Yongju Ye, Yuefang Ren, Jiali Lu, Aixue Chen
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Ovarian Research
Subjects:
LncRNA SNHG12
Polycystic ovarian syndrome
Granulosa cells
MiR-129
MiR-125b
Online Access:https://doi.org/10.1186/s13048-024-01392-6

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