Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection
BackgroundExtra-urogenital infections due to Mycoplasma hominis (M. hominis) are rare, particularly co-infection with Pseudomonas aeruginosa (P. aeruginosa). Herein, we report on a patient who was co-infected and successfully treated despite delayed treatment.Case presentationWe reported the case of...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2023.1159891/full |
| _version_ | 1797836113840177152 |
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| author | Shi-Mei Huang Yu-Rong Tang Ji-Liang Wang Xiao-Zhen Wang Yuan-Yuan Zhang Su-Fei Pan |
| author_facet | Shi-Mei Huang Yu-Rong Tang Ji-Liang Wang Xiao-Zhen Wang Yuan-Yuan Zhang Su-Fei Pan |
| author_sort | Shi-Mei Huang |
| collection | DOAJ |
| description | BackgroundExtra-urogenital infections due to Mycoplasma hominis (M. hominis) are rare, particularly co-infection with Pseudomonas aeruginosa (P. aeruginosa). Herein, we report on a patient who was co-infected and successfully treated despite delayed treatment.Case presentationWe reported the case of a 43-year-old man with M. hominis and P. aeruginosa co-infection after a traffic accident. The patient developed a fever and severe infection despite postoperative antimicrobial therapies. The blood culture of wound tissues was positive for P. aeruginosa. Meanwhile, culturing of blood and wound samples showed pinpoint-sized colonies on blood agar plates and fried-egg-type colonies on mycoplasma medium, which were identified as M. hominis by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA sequencing. Based on antibiotic susceptibility and symptoms, ceftazidime–avibactam and moxifloxacin were administered for P. aeruginosa infection. Meanwhile, after the failure of a series of anti-infective agents, M. hominis and P. aeruginosa co-infection was successfully treated with a minocycline-based regimen and polymyxin B.ConclusionThe co-infection with M. hominis and P. aeruginosa was successfully treated with anti-infective agents despite delayed treatment, providing information for the management of double infection. |
| first_indexed | 2024-04-09T15:04:31Z |
| format | Article |
| id | doaj.art-dabb368eae3c4ba6818eb5b7588873e6 |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-04-09T15:04:31Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-dabb368eae3c4ba6818eb5b7588873e62023-05-01T04:30:22ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882023-05-011310.3389/fcimb.2023.11598911159891Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infectionShi-Mei HuangYu-Rong TangJi-Liang WangXiao-Zhen WangYuan-Yuan ZhangSu-Fei PanBackgroundExtra-urogenital infections due to Mycoplasma hominis (M. hominis) are rare, particularly co-infection with Pseudomonas aeruginosa (P. aeruginosa). Herein, we report on a patient who was co-infected and successfully treated despite delayed treatment.Case presentationWe reported the case of a 43-year-old man with M. hominis and P. aeruginosa co-infection after a traffic accident. The patient developed a fever and severe infection despite postoperative antimicrobial therapies. The blood culture of wound tissues was positive for P. aeruginosa. Meanwhile, culturing of blood and wound samples showed pinpoint-sized colonies on blood agar plates and fried-egg-type colonies on mycoplasma medium, which were identified as M. hominis by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA sequencing. Based on antibiotic susceptibility and symptoms, ceftazidime–avibactam and moxifloxacin were administered for P. aeruginosa infection. Meanwhile, after the failure of a series of anti-infective agents, M. hominis and P. aeruginosa co-infection was successfully treated with a minocycline-based regimen and polymyxin B.ConclusionThe co-infection with M. hominis and P. aeruginosa was successfully treated with anti-infective agents despite delayed treatment, providing information for the management of double infection.https://www.frontiersin.org/articles/10.3389/fcimb.2023.1159891/fullMycoplasma hominisPseudomonas aeruginosacase reportinfectious diseasesinfection |
| spellingShingle | Shi-Mei Huang Yu-Rong Tang Ji-Liang Wang Xiao-Zhen Wang Yuan-Yuan Zhang Su-Fei Pan Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection Frontiers in Cellular and Infection Microbiology Mycoplasma hominis Pseudomonas aeruginosa case report infectious diseases infection |
| title | Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection |
| title_full | Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection |
| title_fullStr | Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection |
| title_full_unstemmed | Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection |
| title_short | Case Report: Double trouble: a rare case of successfully treated Mycoplasma hominis and Pseudomonas aeruginosa co-infection |
| title_sort | case report double trouble a rare case of successfully treated mycoplasma hominis and pseudomonas aeruginosa co infection |
| topic | Mycoplasma hominis Pseudomonas aeruginosa case report infectious diseases infection |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2023.1159891/full |
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