A descriptive study of routine laboratory testing in intensive care unit in nearly 140,000 patient stays
Abstract To describe the relationship between the use of laboratory tests and changes in laboratory parameters in ICU patients is necessary to help optimize routine laboratory testing. A retrospective, descriptive study was conducted on the large eICU-Collaborative Research Database. The relationshi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-25961-1 |
| _version_ | 1811198384920330240 |
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| author | Jérôme Allyn Marjolaine Devineau Matthieu Oliver Guillaume Descombes Nicolas Allou Cyril Ferdynus |
| author_facet | Jérôme Allyn Marjolaine Devineau Matthieu Oliver Guillaume Descombes Nicolas Allou Cyril Ferdynus |
| author_sort | Jérôme Allyn |
| collection | DOAJ |
| description | Abstract To describe the relationship between the use of laboratory tests and changes in laboratory parameters in ICU patients is necessary to help optimize routine laboratory testing. A retrospective, descriptive study was conducted on the large eICU-Collaborative Research Database. The relationship between the use of routine laboratory tests (chemistry and blood counts) and changes in ten common laboratory parameters was studied. Factors associated with laboratory tests were identified in a multivariate regression analysis using generalized estimating equation Poisson models. The study included 138,734 patient stays, with an ICU mortality of 8.97%. For all parameters, the proportion of patients with at least one test decreased from day 0 to day 1 and then gradually increased until the end of the ICU stay. Paradoxically, the results of almost all tests moved toward normal values, and the daily variation in the results of almost all tests decreased over time. The presence of an arterial catheter or teaching hospitals were independently associated with an increase in the number of laboratory tests performed. The paradox of routine laboratory testing should be further explored by assessing the factors that drive the decision to perform routine laboratory testing in ICU and the impact of such testing on patient. |
| first_indexed | 2024-04-12T01:30:08Z |
| format | Article |
| id | doaj.art-dac512b5924d4d03b9ed24fc4ecb525c |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-12T01:30:08Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-dac512b5924d4d03b9ed24fc4ecb525c2022-12-22T03:53:31ZengNature PortfolioScientific Reports2045-23222022-12-0112111010.1038/s41598-022-25961-1A descriptive study of routine laboratory testing in intensive care unit in nearly 140,000 patient staysJérôme Allyn0Marjolaine Devineau1Matthieu Oliver2Guillaume Descombes3Nicolas Allou4Cyril Ferdynus5Intensive Care Unit, Saint-Denis University HospitalIntensive Care Unit, Saint-Denis University HospitalClinical Informatics Department, Saint-Denis University HospitalBiology Laboratory, Saint-Denis University HospitalIntensive Care Unit, Saint-Denis University HospitalClinical Informatics Department, Saint-Denis University HospitalAbstract To describe the relationship between the use of laboratory tests and changes in laboratory parameters in ICU patients is necessary to help optimize routine laboratory testing. A retrospective, descriptive study was conducted on the large eICU-Collaborative Research Database. The relationship between the use of routine laboratory tests (chemistry and blood counts) and changes in ten common laboratory parameters was studied. Factors associated with laboratory tests were identified in a multivariate regression analysis using generalized estimating equation Poisson models. The study included 138,734 patient stays, with an ICU mortality of 8.97%. For all parameters, the proportion of patients with at least one test decreased from day 0 to day 1 and then gradually increased until the end of the ICU stay. Paradoxically, the results of almost all tests moved toward normal values, and the daily variation in the results of almost all tests decreased over time. The presence of an arterial catheter or teaching hospitals were independently associated with an increase in the number of laboratory tests performed. The paradox of routine laboratory testing should be further explored by assessing the factors that drive the decision to perform routine laboratory testing in ICU and the impact of such testing on patient.https://doi.org/10.1038/s41598-022-25961-1 |
| spellingShingle | Jérôme Allyn Marjolaine Devineau Matthieu Oliver Guillaume Descombes Nicolas Allou Cyril Ferdynus A descriptive study of routine laboratory testing in intensive care unit in nearly 140,000 patient stays Scientific Reports |
| title | A descriptive study of routine laboratory testing in intensive care unit in nearly 140,000 patient stays |
| title_full | A descriptive study of routine laboratory testing in intensive care unit in nearly 140,000 patient stays |
| title_fullStr | A descriptive study of routine laboratory testing in intensive care unit in nearly 140,000 patient stays |
| title_full_unstemmed | A descriptive study of routine laboratory testing in intensive care unit in nearly 140,000 patient stays |
| title_short | A descriptive study of routine laboratory testing in intensive care unit in nearly 140,000 patient stays |
| title_sort | descriptive study of routine laboratory testing in intensive care unit in nearly 140 000 patient stays |
| url | https://doi.org/10.1038/s41598-022-25961-1 |
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