Improvement of the bladder perfusion curative effect through tight junction protein degradation induced by magnetic temperature-sensitive hydrogels

Improvement of the bladder perfusion curative effect through tight junction protein degradation induced by magnetic temperature-sensitive hydrogels

Postoperative intravesical instillation of chemotherapy is a routine procedure for non-muscular invasive bladder cancer (NMIBC). However, traditional bladder perfusion methods have insufficient exposure time, resulting in unsatisfactory therapeutic effects. In the present study, a chitosan (CS)-base...

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Bibliographic Details
Main Authors: Xiaoliang Sun, Xinhong Song, Peng Guo, Dong Zhang, Shishuai Zuo, Kang Leng, Yun Liu, Haiyang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
bladder perfusion
pirarubicin
chitosan
sustained release
tight junction
occludin
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.958072/full

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