A fractional order model for the co-interaction of COVID-19 and Hepatitis B virus

Fractional differential equations are beginning to gain widespread usage in modeling physical and biological processes. It is worth mentioning that the standard mathematical models of integer-order derivatives, including nonlinear models, do not constitute suitable framework in many cases. In this w...

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Main Authors: Andrew Omame, Mujahid Abbas, Chibueze P. Onyenegecha
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Results in Physics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221137972200242X
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author Andrew Omame
Mujahid Abbas
Chibueze P. Onyenegecha
author_facet Andrew Omame
Mujahid Abbas
Chibueze P. Onyenegecha
author_sort Andrew Omame
collection DOAJ
description Fractional differential equations are beginning to gain widespread usage in modeling physical and biological processes. It is worth mentioning that the standard mathematical models of integer-order derivatives, including nonlinear models, do not constitute suitable framework in many cases. In this work, a mathematical model for COVID-19 and Hepatitis B Virus (HBV) co-interaction is developed and studied using the Atangana–Baleanu fractional derivative. The necessary conditions of the existence and uniqueness of the solution of the proposed model are studied. The local stability analysis is carried out when the reproduction number is less than one. Using well constructed Lyapunov functions, the disease free and endemic equilibria are proven to be globally asymptotically stable under certain conditions. Employing fixed point theory, the stability of the iterative scheme to approximate the solution of the model is discussed. The model is fitted to real data from the city of Wuhan, China, and important parameters relating to each disease and their co-infection, are estimated from the fitting. The approximate solutions of the model are compared using the integer and fractional order derivatives. The impact of the fractional derivative on the proposed model is also highlighted. The results proven in this paper illustrate that HBV and COVID-19 transmission rates can greatly impact the dynamics of the co-infection of both diseases. It is concluded that to control the co-circulation of both diseases in a population, efforts must be geared towards preventing incident infection with either or both diseases.
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spelling doaj.art-dacaa6d5a4bf4898a27dc7010a4f0f112022-12-22T03:35:13ZengElsevierResults in Physics2211-37972022-06-0137105498A fractional order model for the co-interaction of COVID-19 and Hepatitis B virusAndrew Omame0Mujahid Abbas1Chibueze P. Onyenegecha2Department of Mathematics, Federal University of Technology, Owerri, Nigeria; Abdus Salam School of Mathematical Sciences, Government College University Katchery Road, Lahore 54000, Pakistan; Corresponding author at: Department of Mathematics, Federal University of Technology, Owerri, Nigeria.Department of Mathematics, Government College University Katchery Road, Lahore 54000, Pakistan; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung 40402, TaiwanDepartment of Physics, Federal University of Technology Owerri, NigeriaFractional differential equations are beginning to gain widespread usage in modeling physical and biological processes. It is worth mentioning that the standard mathematical models of integer-order derivatives, including nonlinear models, do not constitute suitable framework in many cases. In this work, a mathematical model for COVID-19 and Hepatitis B Virus (HBV) co-interaction is developed and studied using the Atangana–Baleanu fractional derivative. The necessary conditions of the existence and uniqueness of the solution of the proposed model are studied. The local stability analysis is carried out when the reproduction number is less than one. Using well constructed Lyapunov functions, the disease free and endemic equilibria are proven to be globally asymptotically stable under certain conditions. Employing fixed point theory, the stability of the iterative scheme to approximate the solution of the model is discussed. The model is fitted to real data from the city of Wuhan, China, and important parameters relating to each disease and their co-infection, are estimated from the fitting. The approximate solutions of the model are compared using the integer and fractional order derivatives. The impact of the fractional derivative on the proposed model is also highlighted. The results proven in this paper illustrate that HBV and COVID-19 transmission rates can greatly impact the dynamics of the co-infection of both diseases. It is concluded that to control the co-circulation of both diseases in a population, efforts must be geared towards preventing incident infection with either or both diseases.http://www.sciencedirect.com/science/article/pii/S221137972200242XCOVID-19HBVCo-infectionFractional derivativeLyapunov functionsStability
spellingShingle Andrew Omame
Mujahid Abbas
Chibueze P. Onyenegecha
A fractional order model for the co-interaction of COVID-19 and Hepatitis B virus
Results in Physics
COVID-19
HBV
Co-infection
Fractional derivative
Lyapunov functions
Stability
title A fractional order model for the co-interaction of COVID-19 and Hepatitis B virus
title_full A fractional order model for the co-interaction of COVID-19 and Hepatitis B virus
title_fullStr A fractional order model for the co-interaction of COVID-19 and Hepatitis B virus
title_full_unstemmed A fractional order model for the co-interaction of COVID-19 and Hepatitis B virus
title_short A fractional order model for the co-interaction of COVID-19 and Hepatitis B virus
title_sort fractional order model for the co interaction of covid 19 and hepatitis b virus
topic COVID-19
HBV
Co-infection
Fractional derivative
Lyapunov functions
Stability
url http://www.sciencedirect.com/science/article/pii/S221137972200242X
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