Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population
Background: Oily fish and their extracted oils may be a source of polychlorinated biphenyls (PCBs) which can induce toxic effects on the consumers. The main aim of this survey was estimation of PCBs intake through fish oil-derived dietary supplements and prescription drugs in the Japanese population...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Shahid Sadoughi University of Medical Sciences
2019-12-01
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| Series: | Journal of Food Quality and Hazards Control |
| Subjects: | |
| Online Access: | http://jfqhc.ssu.ac.ir/article-1-631-en.html |
| _version_ | 1818996380235988992 |
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| author | Y. Matsuo K. Nakai I. Sakuma K. Akutsu N. Tatsuta M. Ishiyama T. Higuchi N. Ryuda D. Ueno |
| author_facet | Y. Matsuo K. Nakai I. Sakuma K. Akutsu N. Tatsuta M. Ishiyama T. Higuchi N. Ryuda D. Ueno |
| author_sort | Y. Matsuo |
| collection | DOAJ |
| description | Background: Oily fish and their extracted oils may be a source of polychlorinated biphenyls (PCBs) which can induce toxic effects on the consumers. The main aim of this survey was estimation of PCBs intake through fish oil-derived dietary supplements and prescription drugs in the Japanese population.
Methods: PCBs levels were determined in 20 fish oil-derived dietary supplements and 6 oil-derived prescription drugs from the Japanese market using Gas Chromatography-Mass Spectrometry. Then, the daily exposure to PCBs was estimated. Data were statistically analyzed using JMP software suite.
Results: Totally, 17 of the 26 fish oil-derived products were contaminated with PCBs. The median PCB concentrations in the total set of fish oil-derived products was 2.2 ng/g oil wt. with a range of <MDL-720 ng/g oil wt. The average total daily intake of PCBs was estimated to be ranged from 770 to 2800 ng/day in the Japanese population.
Conclusion: PCBs intakes through fish oil-derived dietary supplements and prescription drugs in the Japanese adults were much lower than tolerable daily intake.
DOI: 10.18502/jfqhc.6.4.1992 |
| first_indexed | 2024-12-20T21:28:49Z |
| format | Article |
| id | doaj.art-dacb6c535a1e42848bf46e2855fab24f |
| institution | Directory Open Access Journal |
| issn | 2345-685X 2345-6825 |
| language | English |
| last_indexed | 2024-12-20T21:28:49Z |
| publishDate | 2019-12-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | Journal of Food Quality and Hazards Control |
| spelling | doaj.art-dacb6c535a1e42848bf46e2855fab24f2022-12-21T19:26:05ZengShahid Sadoughi University of Medical SciencesJournal of Food Quality and Hazards Control2345-685X2345-68252019-12-0164146152Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese PopulationY. Matsuo0K. Nakai1I. Sakuma2K. Akutsu3N. Tatsuta4M. Ishiyama5T. Higuchi6N. Ryuda7D. Ueno8 Graduate School of Agriculture, Saga University, Saga, Japan Department of Development and Environmental Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan Caress Sapporo Hokko Memorial Clinic, Sapporo, Japan Food Chemistry Section 1, Division of Hygienic Chemistry, Osaka Institute of Public Health, Osaka, Japan Department of Development and Environmental Medicine, Graduate School of Medicine, Tohoku University, Sendai, Japan Graduate School of Agriculture, Saga University, Saga, Japan Graduate School of Agriculture, Saga University, Saga, Japan Graduate School of Agriculture, Saga University, Saga, Japan Graduate School of Agriculture, Saga University, Saga, Japan Background: Oily fish and their extracted oils may be a source of polychlorinated biphenyls (PCBs) which can induce toxic effects on the consumers. The main aim of this survey was estimation of PCBs intake through fish oil-derived dietary supplements and prescription drugs in the Japanese population. Methods: PCBs levels were determined in 20 fish oil-derived dietary supplements and 6 oil-derived prescription drugs from the Japanese market using Gas Chromatography-Mass Spectrometry. Then, the daily exposure to PCBs was estimated. Data were statistically analyzed using JMP software suite. Results: Totally, 17 of the 26 fish oil-derived products were contaminated with PCBs. The median PCB concentrations in the total set of fish oil-derived products was 2.2 ng/g oil wt. with a range of <MDL-720 ng/g oil wt. The average total daily intake of PCBs was estimated to be ranged from 770 to 2800 ng/day in the Japanese population. Conclusion: PCBs intakes through fish oil-derived dietary supplements and prescription drugs in the Japanese adults were much lower than tolerable daily intake. DOI: 10.18502/jfqhc.6.4.1992http://jfqhc.ssu.ac.ir/article-1-631-en.htmlpolychlorinated biphenylsfish oilsdietary supplementsprescription drugsrisk assessmentjapan |
| spellingShingle | Y. Matsuo K. Nakai I. Sakuma K. Akutsu N. Tatsuta M. Ishiyama T. Higuchi N. Ryuda D. Ueno Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population Journal of Food Quality and Hazards Control polychlorinated biphenyls fish oils dietary supplements prescription drugs risk assessment japan |
| title | Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population |
| title_full | Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population |
| title_fullStr | Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population |
| title_full_unstemmed | Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population |
| title_short | Estimation of Polychlorinated Biphenyls Intake through Fish Oil-Derived Dietary Supplements and Prescription Drugs in the Japanese Population |
| title_sort | estimation of polychlorinated biphenyls intake through fish oil derived dietary supplements and prescription drugs in the japanese population |
| topic | polychlorinated biphenyls fish oils dietary supplements prescription drugs risk assessment japan |
| url | http://jfqhc.ssu.ac.ir/article-1-631-en.html |
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