Premature neonatal gut microbial community patterns supporting an epithelial TLR-mediated pathway for necrotizing enterocolitis

Premature neonatal gut microbial community patterns supporting an epithelial TLR-mediated pathway for necrotizing enterocolitis

Abstract Background Necrotising enterocolitis (NEC) is a devastating bowel disease, primarily affecting premature infants, with a poorly understood aetiology. Prior studies have found associations in different cases with an overabundance of particular elements of the faecal microbiota (in particular...

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Bibliographic Details
Main Authors: Alexander G. Shaw, Kathleen Sim, Graham Rose, David J. Wooldridge, Ming-Shi Li, Raju V. Misra, Saheer Gharbia, J. Simon Kroll
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Microbiology
Subjects:
Metagenome
Necrotising enterocolitis
Premature infant
Microbiome
TLR4
TLR9
Online Access:https://doi.org/10.1186/s12866-021-02285-0

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