Physical design of a compact injector for synchrotron-based proton therapy
A compact room-temperature linear injector has been purposed to accelerate an 18.0 mA proton beam to 7.0 MeV for synchrotron-based proton therapy. The total length is appropriately 5 m. It mainly consists of a 3.01 m radio frequency quadrupole (RFQ) and a 0.82 m compact interdigital H-mode drift tub...
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| Format: | Article |
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Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Physics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphy.2023.1201158/full |
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| author | Jian Qiao Jian Qiao Jian Qiao Jian Qiao Nan Yan Nan Yan Zike Huang Zike Huang Zike Huang Zike Huang Yang Zhong Yang Zhong Yang Zhong Yang Zhong Jiazhou Wang Jiazhou Wang Jiazhou Wang Jiazhou Wang Xiucui Xie Yuehu Pu Yuehu Pu Yuehu Pu Weigang Hu Weigang Hu Weigang Hu Weigang Hu |
| author_facet | Jian Qiao Jian Qiao Jian Qiao Jian Qiao Nan Yan Nan Yan Zike Huang Zike Huang Zike Huang Zike Huang Yang Zhong Yang Zhong Yang Zhong Yang Zhong Jiazhou Wang Jiazhou Wang Jiazhou Wang Jiazhou Wang Xiucui Xie Yuehu Pu Yuehu Pu Yuehu Pu Weigang Hu Weigang Hu Weigang Hu Weigang Hu |
| author_sort | Jian Qiao |
| collection | DOAJ |
| description | A compact room-temperature linear injector has been purposed to accelerate an 18.0 mA proton beam to 7.0 MeV for synchrotron-based proton therapy. The total length is appropriately 5 m. It mainly consists of a 3.01 m radio frequency quadrupole (RFQ) and a 0.82 m compact interdigital H-mode drift tube linac (IH-DTL) structure. Based on a fast-bunching strategy, the RFQ, operated at 325 MHz, accelerates protons to 3.0 MeV. The phase advances have been taken into consideration, and parametric resonance has been carefully avoided by adjusting the vane parameters. After the modulation of the transverse and longitudinal phase advances and a compact external quadrupole triplet, the proton beam is injected into the subsequent IH-DTL. Based on modified Kombinierte Null Grad Strukter (KONUS) beam dynamics, it accelerates protons up to 7.0 MeV, which is composed of a re-bunching section and an accelerating section. The accelerating gradient reaches 4.88 MV/m. The overall dynamic simulation results show that the whole accelerating gradient reaches up to 1.62 MV/m with a transmission efficiency above 95%. The transverse and longitudinal normalized RMS emittances at the exit of the DTL are 0.23 π mm·mrad and 2.216 π keV/u·ns, which meet the synchrotron injection requirements. The details of the specific design of this injector are presented in this paper. |
| first_indexed | 2024-03-13T08:06:44Z |
| format | Article |
| id | doaj.art-dacdfbbca03d4d5dbfdd7b12f544911e |
| institution | Directory Open Access Journal |
| issn | 2296-424X |
| language | English |
| last_indexed | 2024-03-13T08:06:44Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Physics |
| spelling | doaj.art-dacdfbbca03d4d5dbfdd7b12f544911e2023-06-01T05:05:23ZengFrontiers Media S.A.Frontiers in Physics2296-424X2023-06-011110.3389/fphy.2023.12011581201158Physical design of a compact injector for synchrotron-based proton therapyJian Qiao0Jian Qiao1Jian Qiao2Jian Qiao3Nan Yan4Nan Yan5Zike Huang6Zike Huang7Zike Huang8Zike Huang9Yang Zhong10Yang Zhong11Yang Zhong12Yang Zhong13Jiazhou Wang14Jiazhou Wang15Jiazhou Wang16Jiazhou Wang17Xiucui Xie18Yuehu Pu19Yuehu Pu20Yuehu Pu21Weigang Hu22Weigang Hu23Weigang Hu24Weigang Hu25Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, ChinaDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, ChinaShanghai Clinical Research Center for Radiation Oncology, Shanghai, ChinaShanghai Key Laboratory of Radiation Oncology, Shanghai, ChinaShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, ChinaUniversity of the Chinese Academy of Sciences, Beijing, ChinaDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, ChinaDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, ChinaShanghai Clinical Research Center for Radiation Oncology, Shanghai, ChinaShanghai Key Laboratory of Radiation Oncology, Shanghai, ChinaDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, ChinaDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, ChinaShanghai Clinical Research Center for Radiation Oncology, Shanghai, ChinaShanghai Key Laboratory of Radiation Oncology, Shanghai, ChinaDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, ChinaDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, ChinaShanghai Clinical Research Center for Radiation Oncology, Shanghai, ChinaShanghai Key Laboratory of Radiation Oncology, Shanghai, ChinaShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, ChinaWest China Hospital, Sichuan University, Chengdu, ChinaMedical Device Regulatory Research and Evaluation Centre, West China Hospital, Sichuan University, Chengdu, ChinaMedical Equipment Innovation Research Center, Med+X Center for Manufacturing, West China School of Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, ChinaDepartment of Oncology, Shanghai Medical College, Fudan University, Shanghai, ChinaShanghai Clinical Research Center for Radiation Oncology, Shanghai, ChinaShanghai Key Laboratory of Radiation Oncology, Shanghai, ChinaA compact room-temperature linear injector has been purposed to accelerate an 18.0 mA proton beam to 7.0 MeV for synchrotron-based proton therapy. The total length is appropriately 5 m. It mainly consists of a 3.01 m radio frequency quadrupole (RFQ) and a 0.82 m compact interdigital H-mode drift tube linac (IH-DTL) structure. Based on a fast-bunching strategy, the RFQ, operated at 325 MHz, accelerates protons to 3.0 MeV. The phase advances have been taken into consideration, and parametric resonance has been carefully avoided by adjusting the vane parameters. After the modulation of the transverse and longitudinal phase advances and a compact external quadrupole triplet, the proton beam is injected into the subsequent IH-DTL. Based on modified Kombinierte Null Grad Strukter (KONUS) beam dynamics, it accelerates protons up to 7.0 MeV, which is composed of a re-bunching section and an accelerating section. The accelerating gradient reaches 4.88 MV/m. The overall dynamic simulation results show that the whole accelerating gradient reaches up to 1.62 MV/m with a transmission efficiency above 95%. The transverse and longitudinal normalized RMS emittances at the exit of the DTL are 0.23 π mm·mrad and 2.216 π keV/u·ns, which meet the synchrotron injection requirements. The details of the specific design of this injector are presented in this paper.https://www.frontiersin.org/articles/10.3389/fphy.2023.1201158/fullproton therapycompact linear injector4-vane RFQKONUS dynamicsIH-DTL |
| spellingShingle | Jian Qiao Jian Qiao Jian Qiao Jian Qiao Nan Yan Nan Yan Zike Huang Zike Huang Zike Huang Zike Huang Yang Zhong Yang Zhong Yang Zhong Yang Zhong Jiazhou Wang Jiazhou Wang Jiazhou Wang Jiazhou Wang Xiucui Xie Yuehu Pu Yuehu Pu Yuehu Pu Weigang Hu Weigang Hu Weigang Hu Weigang Hu Physical design of a compact injector for synchrotron-based proton therapy Frontiers in Physics proton therapy compact linear injector 4-vane RFQ KONUS dynamics IH-DTL |
| title | Physical design of a compact injector for synchrotron-based proton therapy |
| title_full | Physical design of a compact injector for synchrotron-based proton therapy |
| title_fullStr | Physical design of a compact injector for synchrotron-based proton therapy |
| title_full_unstemmed | Physical design of a compact injector for synchrotron-based proton therapy |
| title_short | Physical design of a compact injector for synchrotron-based proton therapy |
| title_sort | physical design of a compact injector for synchrotron based proton therapy |
| topic | proton therapy compact linear injector 4-vane RFQ KONUS dynamics IH-DTL |
| url | https://www.frontiersin.org/articles/10.3389/fphy.2023.1201158/full |
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