Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cells

In this communication, CdO doped with Ni was employed for new biological applications as an anti-cancer. However, the prepared system needed to be identified through the typical characterizations. The Cd1-xNixO system was utilized by the Co-precipitate calcinations method. To enhance the availabilit...

Full description

Bibliographic Details
Main Authors: Aliaa Mazhar, Nourhan S. Elkholy, N.M. Yousif, M.S. Shalaby
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623004435
_version_ 1797398658716532736
author Aliaa Mazhar
Nourhan S. Elkholy
N.M. Yousif
M.S. Shalaby
author_facet Aliaa Mazhar
Nourhan S. Elkholy
N.M. Yousif
M.S. Shalaby
author_sort Aliaa Mazhar
collection DOAJ
description In this communication, CdO doped with Ni was employed for new biological applications as an anti-cancer. However, the prepared system needed to be identified through the typical characterizations. The Cd1-xNixO system was utilized by the Co-precipitate calcinations method. To enhance the availability and processability of the materials, and be as sure of achieving the nanomaterials, X-ray diffraction (XRD) analysis indicated exhibited a polycrystalline structure with distinctive structural parameters—however, the single phase Cd1-xNixO exhibits nanoscale material.The optical band gap of the samples was determined using diffused reflectance spectra analysis, revealing Eg values of 2.19 eV for undoped CdO and ranging from 1.62 to 2.12 eV for Ni-doped CdO samples at varying concentrations of Ni.Thermal stability measurements were conducted using a Thermogravimetric analyzer (TGA) in the temperature range from room temperature to 1000 °C at a rate of 15 deg/min. Furthermore, the cytotoxicity effect of the synthesized Cd1-xNixO samples was evaluated against four different cancer cell lines: breast carcinoma (MCF-7), human hepatoblastoma (HepG2), human lung adenocarcinoma (A549), and human breast cancer (MDA-MB-231).Overall, these findings provide valuable insights into the properties of Cd1-xNixO nanostructures synthesized via the Co-precipitate calcinations method and their potential applications in various fields, including optoelectronics and biomedical sciences.
first_indexed 2024-03-09T01:28:46Z
format Article
id doaj.art-dacf4e054fac44a0a2ab3a4444d4b9b1
institution Directory Open Access Journal
issn 2211-7156
language English
last_indexed 2024-03-09T01:28:46Z
publishDate 2023-12-01
publisher Elsevier
record_format Article
series Results in Chemistry
spelling doaj.art-dacf4e054fac44a0a2ab3a4444d4b9b12023-12-10T06:15:37ZengElsevierResults in Chemistry2211-71562023-12-016101204Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cellsAliaa Mazhar0Nourhan S. Elkholy1N.M. Yousif2M.S. Shalaby3Radiation Physics Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, EgyptMedical Biophysics Division, Physics Department, Faculty of Science, Helwan University, Cairo, Egypt, Nawah Scientific Center, Cairo, Egypt; Solid-State Physics and Accelerators Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, B.O. Box 29, Cairo, EgyptSolid-State Physics and Accelerators Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, B.O. Box 29, Cairo, EgyptSolid-State Physics and Accelerators Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, B.O. Box 29, Cairo, Egypt; Corresponding author.In this communication, CdO doped with Ni was employed for new biological applications as an anti-cancer. However, the prepared system needed to be identified through the typical characterizations. The Cd1-xNixO system was utilized by the Co-precipitate calcinations method. To enhance the availability and processability of the materials, and be as sure of achieving the nanomaterials, X-ray diffraction (XRD) analysis indicated exhibited a polycrystalline structure with distinctive structural parameters—however, the single phase Cd1-xNixO exhibits nanoscale material.The optical band gap of the samples was determined using diffused reflectance spectra analysis, revealing Eg values of 2.19 eV for undoped CdO and ranging from 1.62 to 2.12 eV for Ni-doped CdO samples at varying concentrations of Ni.Thermal stability measurements were conducted using a Thermogravimetric analyzer (TGA) in the temperature range from room temperature to 1000 °C at a rate of 15 deg/min. Furthermore, the cytotoxicity effect of the synthesized Cd1-xNixO samples was evaluated against four different cancer cell lines: breast carcinoma (MCF-7), human hepatoblastoma (HepG2), human lung adenocarcinoma (A549), and human breast cancer (MDA-MB-231).Overall, these findings provide valuable insights into the properties of Cd1-xNixO nanostructures synthesized via the Co-precipitate calcinations method and their potential applications in various fields, including optoelectronics and biomedical sciences.http://www.sciencedirect.com/science/article/pii/S2211715623004435NanopowderNi doped CdO nano-structureXRDDiffused reflectanceOptical constantsAnd breast cancer (MDA-MB-231)
spellingShingle Aliaa Mazhar
Nourhan S. Elkholy
N.M. Yousif
M.S. Shalaby
Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cells
Results in Chemistry
Nanopowder
Ni doped CdO nano-structure
XRD
Diffused reflectance
Optical constants
And breast cancer (MDA-MB-231)
title Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cells
title_full Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cells
title_fullStr Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cells
title_full_unstemmed Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cells
title_short Investigations of Structural, Optical, Thermal, and spectroscopic characteristics of CdO-Ni nanoparticles employed in anti-cancer activities for cancer cells
title_sort investigations of structural optical thermal and spectroscopic characteristics of cdo ni nanoparticles employed in anti cancer activities for cancer cells
topic Nanopowder
Ni doped CdO nano-structure
XRD
Diffused reflectance
Optical constants
And breast cancer (MDA-MB-231)
url http://www.sciencedirect.com/science/article/pii/S2211715623004435
work_keys_str_mv AT aliaamazhar investigationsofstructuralopticalthermalandspectroscopiccharacteristicsofcdoninanoparticlesemployedinanticanceractivitiesforcancercells
AT nourhanselkholy investigationsofstructuralopticalthermalandspectroscopiccharacteristicsofcdoninanoparticlesemployedinanticanceractivitiesforcancercells
AT nmyousif investigationsofstructuralopticalthermalandspectroscopiccharacteristicsofcdoninanoparticlesemployedinanticanceractivitiesforcancercells
AT msshalaby investigationsofstructuralopticalthermalandspectroscopiccharacteristicsofcdoninanoparticlesemployedinanticanceractivitiesforcancercells