Cole Relaxation Frequency as a Prognostic Parameter for Breast Cancer
We previously reported successful classification of breast cancer versus benign tissue using the Cole relaxation frequency measured on tissue excised during breast surgery as part of a study at two urban hospitals in the U.S. Midwest. Using that health system’s cancer registry, we have discovered re...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Advocate Aurora Health
2020-10-01
|
| Series: | Journal of Patient-Centered Research and Reviews |
| Subjects: | |
| Online Access: | https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=1794&context=jpcrr |
| _version_ | 1797720225356972032 |
|---|---|
| author | William D. Gregory Shahila Mehboob Christie John Shell Georges J. Nahhas Maharaj Singh Wendy Mikkelson |
| author_facet | William D. Gregory Shahila Mehboob Christie John Shell Georges J. Nahhas Maharaj Singh Wendy Mikkelson |
| author_sort | William D. Gregory |
| collection | DOAJ |
| description | We previously reported successful classification of breast cancer versus benign tissue using the Cole relaxation frequency measured on tissue excised during breast surgery as part of a study at two urban hospitals in the U.S. Midwest. Using that health system’s cancer registry, we have discovered retrospectively that outcomes for patients who participated in the initial study can be classified correctly in 3 well-differentiated categories: nonrecurrent (NR); recurrent with no metastasis (RNM); and recurrent with metastasis (RM). As Cole relaxation frequency increases, the classification moves from NR to RNM and finally to RM. Multivariate analysis showed a significant association of “time-cancer-free” for all patients in these recurrent categories, with P-values ranging between 0.0001 to 0.0047. Thus, this follow-up report shows the potential feasibility of using Cole relaxation frequency as a prognostic parameter in a larger prospective study. |
| first_indexed | 2024-03-12T09:16:23Z |
| format | Article |
| id | doaj.art-dad7193bba214bd1bea7fc1594263961 |
| institution | Directory Open Access Journal |
| issn | 2330-0698 |
| language | English |
| last_indexed | 2024-03-12T09:16:23Z |
| publishDate | 2020-10-01 |
| publisher | Advocate Aurora Health |
| record_format | Article |
| series | Journal of Patient-Centered Research and Reviews |
| spelling | doaj.art-dad7193bba214bd1bea7fc15942639612023-09-02T14:48:18ZengAdvocate Aurora HealthJournal of Patient-Centered Research and Reviews2330-06982020-10-017434334810.17294/2330-0698.1794Cole Relaxation Frequency as a Prognostic Parameter for Breast CancerWilliam D. Gregory0Shahila Mehboob Christie1John Shell2Georges J. Nahhas3Maharaj Singh4Wendy Mikkelson 5NovaScan, Inc., Milwaukee, WI; University of Wisconsin-Milwaukee, Milwaukee, WINovaScan, Inc., Milwaukee, WINovaScan, Inc., Milwaukee, WIMedical University of South Carolina, Charleston, SCMarquette University School of Dentistry, Milwaukee, WI; Advocate Aurora Health, Milwaukee WIAurora St. Luke’s Medical Center, Milwaukee, WIWe previously reported successful classification of breast cancer versus benign tissue using the Cole relaxation frequency measured on tissue excised during breast surgery as part of a study at two urban hospitals in the U.S. Midwest. Using that health system’s cancer registry, we have discovered retrospectively that outcomes for patients who participated in the initial study can be classified correctly in 3 well-differentiated categories: nonrecurrent (NR); recurrent with no metastasis (RNM); and recurrent with metastasis (RM). As Cole relaxation frequency increases, the classification moves from NR to RNM and finally to RM. Multivariate analysis showed a significant association of “time-cancer-free” for all patients in these recurrent categories, with P-values ranging between 0.0001 to 0.0047. Thus, this follow-up report shows the potential feasibility of using Cole relaxation frequency as a prognostic parameter in a larger prospective study.https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=1794&context=jpcrrcole relaxation frequencybreast cancerprognosisbioelectrical impedancerecurrence |
| spellingShingle | William D. Gregory Shahila Mehboob Christie John Shell Georges J. Nahhas Maharaj Singh Wendy Mikkelson Cole Relaxation Frequency as a Prognostic Parameter for Breast Cancer Journal of Patient-Centered Research and Reviews cole relaxation frequency breast cancer prognosis bioelectrical impedance recurrence |
| title | Cole Relaxation Frequency as a Prognostic Parameter for Breast Cancer |
| title_full | Cole Relaxation Frequency as a Prognostic Parameter for Breast Cancer |
| title_fullStr | Cole Relaxation Frequency as a Prognostic Parameter for Breast Cancer |
| title_full_unstemmed | Cole Relaxation Frequency as a Prognostic Parameter for Breast Cancer |
| title_short | Cole Relaxation Frequency as a Prognostic Parameter for Breast Cancer |
| title_sort | cole relaxation frequency as a prognostic parameter for breast cancer |
| topic | cole relaxation frequency breast cancer prognosis bioelectrical impedance recurrence |
| url | https://institutionalrepository.aah.org/cgi/viewcontent.cgi?article=1794&context=jpcrr |
| work_keys_str_mv | AT williamdgregory colerelaxationfrequencyasaprognosticparameterforbreastcancer AT shahilamehboobchristie colerelaxationfrequencyasaprognosticparameterforbreastcancer AT johnshell colerelaxationfrequencyasaprognosticparameterforbreastcancer AT georgesjnahhas colerelaxationfrequencyasaprognosticparameterforbreastcancer AT maharajsingh colerelaxationfrequencyasaprognosticparameterforbreastcancer AT wendymikkelson colerelaxationfrequencyasaprognosticparameterforbreastcancer |