Role of methyltransferase like 3 regulating pri-miR-21 methylation in renal fibrosis of diabetes nephropathy

Role of methyltransferase like 3 regulating pri-miR-21 methylation in renal fibrosis of diabetes nephropathy

Objective·To investigate the role of methyltransferase like 3 (METTL3) acting on N6-methyladenosine (m6A) and regulating pri-miR-21 methylation in the renal fibrosis of diabetic nephropathy (DN).Methods·Eight-week-old male db/db mice were used as DN models, and db/m mice were used as controls. The m...

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Bibliographic Details
Main Authors:	WU Jiajin, ZHONG Chen, LI Dawei, CHEN Ruoyang, QU Junwen, ZHANG Ming
Format:	Article
Language:	zho
Published:	Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2023-01-01
Series:	Shanghai Jiaotong Daxue xuebao. Yixue ban
Subjects:	diabetic nephropathy (dn) renal fibrosis n6-methyladenosine (m6a) methyltransferase like 3 (mettl3) pri-mir-21 mir-21
Online Access:	https://xuebao.shsmu.edu.cn/article/2023/1674-8115/1674-8115-2023-43-1-1.shtml

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