EGF-Dependent Activation of ELK1 Contributes to the Induction of CLDND1 Expression Involved in Tight Junction Formation

EGF-Dependent Activation of ELK1 Contributes to the Induction of CLDND1 Expression Involved in Tight Junction Formation

Claudin proteins are intercellular adhesion molecules. Increased claudin domain-containing 1 (CLDND1) expression is associated with the malignant transformation of estrogen receptor-negative breast cancer cells with low sensitivity to hormone therapy. Abnormal CLDND1 expression is also implicated in...

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Bibliographic Details
Main Authors: Hiroshi Matsuoka, Alice Yamaoka, Takahiro Hamashima, Akiho Shima, Marin Kosako, Yuma Tahara, Jun Kamishikiryo, Akihiro Michihara
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
claudin domain-containing 1
gefitinib
epidermal growth factor receptor
ETS domain-containing protein-1
tight junction
anticancer
Online Access:https://www.mdpi.com/2227-9059/10/8/1792

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