The origin and activities of IgA1-containing immune complexes in IgA nephropathy

The origin and activities of IgA1-containing immune complexes in IgA nephropathy

IgA nephropathy is the most common primary glomerulonephritis, frequently leading to end-stage renal disease, as there is no disease-specific therapy. IgA nephropathy is diagnosed from pathological assessment of a renal biopsy specimen based on predominant or co-dominant IgA-containing immunodeposit...

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Bibliographic Details
Main Authors: Barbora eKnoppova, Colin eReily, Nicolas eMaillard, Dana V. Rizk, Zina eMoldoveanu, Jiri eMestecky, Milan eRaska, Matthew B. Renfrow, Bruce A. Julian, Jan eNovak
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Immunology
Subjects:
Autoantibodies
Complement C3
IgA
immune complexes
nephropathy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00117/full

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