Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles
A highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular iodine under ultrasonic conditions to give 5-(ben...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2017-02-01
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| Series: | Green Processing and Synthesis |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/gps-2016-0099 |
| _version_ | 1819124847917137920 |
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| author | Kumar Surender Sharma Dinesh Kumar |
| author_facet | Kumar Surender Sharma Dinesh Kumar |
| author_sort | Kumar Surender |
| collection | DOAJ |
| description | A highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular iodine under ultrasonic conditions to give 5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles, which was further cyclised using Eaton’s reagent under microwave conditions to give 5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles. |
| first_indexed | 2024-12-22T07:30:45Z |
| format | Article |
| id | doaj.art-dae8d7994c324276be960e2b14b3fb57 |
| institution | Directory Open Access Journal |
| issn | 2191-9542 2191-9550 |
| language | English |
| last_indexed | 2024-12-22T07:30:45Z |
| publishDate | 2017-02-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Green Processing and Synthesis |
| spelling | doaj.art-dae8d7994c324276be960e2b14b3fb572022-12-21T18:34:02ZengDe GruyterGreen Processing and Synthesis2191-95422191-95502017-02-0161737710.1515/gps-2016-0099Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazolesKumar Surender0Sharma Dinesh Kumar1Department of Chemistry, Technological Institute of Textile and Sciences, Bhiwani, 127021, IndiaDepartment of Chemistry, Kishanlal Public College, Rewari, 123401, IndiaA highly efficient, eco-friendly and one-pot synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles was developed involving the reaction of 2-acetyl benzofurans and 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole in the presence of molecular iodine under ultrasonic conditions to give 5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles, which was further cyclised using Eaton’s reagent under microwave conditions to give 5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles.https://doi.org/10.1515/gps-2016-00995-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles5-mercapto-3-(4-chlorophenyl)-1,2,4triazolemicrowave conditionsultrasonic conditions |
| spellingShingle | Kumar Surender Sharma Dinesh Kumar Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles Green Processing and Synthesis 5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles 5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole microwave conditions ultrasonic conditions |
| title | Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles |
| title_full | Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles |
| title_fullStr | Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles |
| title_full_unstemmed | Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles |
| title_short | Ultrasound promoted green synthesis of benzofuran substituted thiazolo[3,2-b][1,2,4]triazoles |
| title_sort | ultrasound promoted green synthesis of benzofuran substituted thiazolo 3 2 b 1 2 4 triazoles |
| topic | 5-(benzofuran-2-yl)-2-(4-chlorophenyl)thiazolo[3,2-b][1,2,4]triazoles 5-(benzofuran-2-yl)-acylthio-3-(4-chlorophenyl)-1,2,4triazoles 5-mercapto-3-(4-chlorophenyl)-1,2,4triazole microwave conditions ultrasonic conditions |
| url | https://doi.org/10.1515/gps-2016-0099 |
| work_keys_str_mv | AT kumarsurender ultrasoundpromotedgreensynthesisofbenzofuransubstitutedthiazolo32b124triazoles AT sharmadineshkumar ultrasoundpromotedgreensynthesisofbenzofuransubstitutedthiazolo32b124triazoles |