Severe disseminated primary varicella in a patient on long term inhaled corticosteroids

Abstract Disseminated primary varicella infection can carry risks of significant morbidity and mortality particularly in immunocompromised populations. Routine, funded childhood vaccination against varicella has significantly reduced associated hospitalization and deaths, however, uptake and efficac...

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Bibliographic Details
Main Authors: James P. Pham, Greta Beale, Mahdieh Gorji, Benjamin Thompson, Suhel Al‐Soufi, Emily Stone
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Respirology Case Reports
Subjects:
Online Access:https://doi.org/10.1002/rcr2.1010
Description
Summary:Abstract Disseminated primary varicella infection can carry risks of significant morbidity and mortality particularly in immunocompromised populations. Routine, funded childhood vaccination against varicella has significantly reduced associated hospitalization and deaths, however, uptake and efficacy among adults is unknown. We present a case of disseminated primary varicella infection (including rash, pneumonitis, hepatitis and thrombocytopenia) in an immunocompetent patient on long term inhaled corticosteroids for asthma. This case highlights potential risk factors for severe varicella which require further study in adults and raises the need to discuss vaccination in at risk groups including appropriate counselling in those who may be at higher risk.
ISSN:2051-3380