Severe disseminated primary varicella in a patient on long term inhaled corticosteroids
Abstract Disseminated primary varicella infection can carry risks of significant morbidity and mortality particularly in immunocompromised populations. Routine, funded childhood vaccination against varicella has significantly reduced associated hospitalization and deaths, however, uptake and efficac...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-09-01
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| Series: | Respirology Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rcr2.1010 |
| _version_ | 1817998214087835648 |
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| author | James P. Pham Greta Beale Mahdieh Gorji Benjamin Thompson Suhel Al‐Soufi Emily Stone |
| author_facet | James P. Pham Greta Beale Mahdieh Gorji Benjamin Thompson Suhel Al‐Soufi Emily Stone |
| author_sort | James P. Pham |
| collection | DOAJ |
| description | Abstract Disseminated primary varicella infection can carry risks of significant morbidity and mortality particularly in immunocompromised populations. Routine, funded childhood vaccination against varicella has significantly reduced associated hospitalization and deaths, however, uptake and efficacy among adults is unknown. We present a case of disseminated primary varicella infection (including rash, pneumonitis, hepatitis and thrombocytopenia) in an immunocompetent patient on long term inhaled corticosteroids for asthma. This case highlights potential risk factors for severe varicella which require further study in adults and raises the need to discuss vaccination in at risk groups including appropriate counselling in those who may be at higher risk. |
| first_indexed | 2024-04-14T02:50:42Z |
| format | Article |
| id | doaj.art-daea4c98e2ba4e10b9e3648a37bb0917 |
| institution | Directory Open Access Journal |
| issn | 2051-3380 |
| language | English |
| last_indexed | 2024-04-14T02:50:42Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj.art-daea4c98e2ba4e10b9e3648a37bb09172022-12-22T02:16:19ZengWileyRespirology Case Reports2051-33802022-09-01109n/an/a10.1002/rcr2.1010Severe disseminated primary varicella in a patient on long term inhaled corticosteroidsJames P. Pham0Greta Beale1Mahdieh Gorji2Benjamin Thompson3Suhel Al‐Soufi4Emily Stone5Department of Thoracic Medicine and Lung Transplantation St Vincent's Hospital Sydney, School of Clinical Medicine, UNSW Medicine and Health St Vincent's Hospital Darlinghurst New South Wales AustraliaDepartment of Thoracic Medicine and Lung Transplantation St Vincent's Hospital Sydney, School of Clinical Medicine, UNSW Medicine and Health St Vincent's Hospital Darlinghurst New South Wales AustraliaDermatology Department Liverpool Hospital Sydney New South Wales AustraliaDermatology Department Liverpool Hospital Sydney New South Wales AustraliaIntensive Care Unit St Vincent's Hospital Sydney New South Wales AustraliaDepartment of Thoracic Medicine and Lung Transplantation St Vincent's Hospital Sydney, School of Clinical Medicine, UNSW Medicine and Health St Vincent's Hospital Darlinghurst New South Wales AustraliaAbstract Disseminated primary varicella infection can carry risks of significant morbidity and mortality particularly in immunocompromised populations. Routine, funded childhood vaccination against varicella has significantly reduced associated hospitalization and deaths, however, uptake and efficacy among adults is unknown. We present a case of disseminated primary varicella infection (including rash, pneumonitis, hepatitis and thrombocytopenia) in an immunocompetent patient on long term inhaled corticosteroids for asthma. This case highlights potential risk factors for severe varicella which require further study in adults and raises the need to discuss vaccination in at risk groups including appropriate counselling in those who may be at higher risk.https://doi.org/10.1002/rcr2.1010asthmalong term inhaled corticosteroidsvaricella |
| spellingShingle | James P. Pham Greta Beale Mahdieh Gorji Benjamin Thompson Suhel Al‐Soufi Emily Stone Severe disseminated primary varicella in a patient on long term inhaled corticosteroids Respirology Case Reports asthma long term inhaled corticosteroids varicella |
| title | Severe disseminated primary varicella in a patient on long term inhaled corticosteroids |
| title_full | Severe disseminated primary varicella in a patient on long term inhaled corticosteroids |
| title_fullStr | Severe disseminated primary varicella in a patient on long term inhaled corticosteroids |
| title_full_unstemmed | Severe disseminated primary varicella in a patient on long term inhaled corticosteroids |
| title_short | Severe disseminated primary varicella in a patient on long term inhaled corticosteroids |
| title_sort | severe disseminated primary varicella in a patient on long term inhaled corticosteroids |
| topic | asthma long term inhaled corticosteroids varicella |
| url | https://doi.org/10.1002/rcr2.1010 |
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