Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy
Aims A cardiopulmonary exercise test (CPET) is the gold standard to evaluate symptom-limiting exercise intolerance, while continuous laryngoscopy performed during exercise (CLE) is required to diagnose exercise-induced laryngeal obstruction. Combining CPET with CLE would save time and resources; how...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2021-02-01
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| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/7/1/00825-2020.full |
| _version_ | 1818863556695687168 |
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| author | Mette Engan Ida Jansrud Hammer Marianne Bekken Thomas Halvorsen Zoe Louise Fretheim-Kelly Maria Vollsæter Lars Peder Vatshelle Bovim Ola Drange Røksund Hege Clemm |
| author_facet | Mette Engan Ida Jansrud Hammer Marianne Bekken Thomas Halvorsen Zoe Louise Fretheim-Kelly Maria Vollsæter Lars Peder Vatshelle Bovim Ola Drange Røksund Hege Clemm |
| author_sort | Mette Engan |
| collection | DOAJ |
| description | Aims
A cardiopulmonary exercise test (CPET) is the gold standard to evaluate symptom-limiting exercise intolerance, while continuous laryngoscopy performed during exercise (CLE) is required to diagnose exercise-induced laryngeal obstruction. Combining CPET with CLE would save time and resources; however, the CPET data may be distorted by the extra equipment. We therefore aimed to study whether CPET with CLE influences peak oxygen uptake (V′O2peak) and other gas exchange parameters when compared to a regular CPET.
Methods
Forty healthy athletes without exercise-related breathing problems, 15–35 years of age, performed CPET to peak exercise with and without an added CLE set-up, in randomised order 2–4 days apart, applying an identical computerised treadmill protocol.
Results
At peak exercise, the mean difference (95% confidence interval) between CPET with and without extra CLE set-up for V′O2peak, respiratory exchange ratio (RER), minute ventilation (V′E) and heart rate (HR) was 0.2 (−0.4 to 0.8) mL·kg−1·min−1, 0.01(−0.007 to 0.027) units, 2.6 (−1.3 to 6.5) L·min−1 and 1.4 (−0.8 to 3.5) beats·min−1, respectively. Agreement (95% limits of agreement) for V′O2peak, RER and V′E was 0.2 (±3.7) mL·kg−1·min−1, 0.01 (±0.10) units and 2.6 (±24.0) L·min−1, respectively. No systematic or proportional bias was found except for the completed distance, which was 49 m (95% CI 16 to 82 m) longer during CPET.
Conclusion
Parameters of gas exchange, including V′O2peak and RER, obtained from a maximal CPET performed with the extra CLE set-up can be used interchangeably with data obtained from standard CPET, thus preventing unnecessary additional testing. |
| first_indexed | 2024-12-19T10:17:39Z |
| format | Article |
| id | doaj.art-daedbeb52e7e44e497bd5d1f75de2889 |
| institution | Directory Open Access Journal |
| issn | 2312-0541 |
| language | English |
| last_indexed | 2024-12-19T10:17:39Z |
| publishDate | 2021-02-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | ERJ Open Research |
| spelling | doaj.art-daedbeb52e7e44e497bd5d1f75de28892022-12-21T20:26:10ZengEuropean Respiratory SocietyERJ Open Research2312-05412021-02-017110.1183/23120541.00825-202000825-2020Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopyMette Engan0Ida Jansrud Hammer1Marianne Bekken2Thomas Halvorsen3Zoe Louise Fretheim-Kelly4Maria Vollsæter5Lars Peder Vatshelle Bovim6Ola Drange Røksund7Hege Clemm8 Dept of Pediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway Dept of Pediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway Dept of Clinical Science, University of Bergen, Bergen, Norway Dept of Pediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway Dept of Clinical Science, University of Bergen, Bergen, Norway Dept of Pediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway Faculty of Health and Social Sciences, Western Norway University of Applied Sciences, Bergen, Norway Dept of Pediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway Dept of Pediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway Aims A cardiopulmonary exercise test (CPET) is the gold standard to evaluate symptom-limiting exercise intolerance, while continuous laryngoscopy performed during exercise (CLE) is required to diagnose exercise-induced laryngeal obstruction. Combining CPET with CLE would save time and resources; however, the CPET data may be distorted by the extra equipment. We therefore aimed to study whether CPET with CLE influences peak oxygen uptake (V′O2peak) and other gas exchange parameters when compared to a regular CPET. Methods Forty healthy athletes without exercise-related breathing problems, 15–35 years of age, performed CPET to peak exercise with and without an added CLE set-up, in randomised order 2–4 days apart, applying an identical computerised treadmill protocol. Results At peak exercise, the mean difference (95% confidence interval) between CPET with and without extra CLE set-up for V′O2peak, respiratory exchange ratio (RER), minute ventilation (V′E) and heart rate (HR) was 0.2 (−0.4 to 0.8) mL·kg−1·min−1, 0.01(−0.007 to 0.027) units, 2.6 (−1.3 to 6.5) L·min−1 and 1.4 (−0.8 to 3.5) beats·min−1, respectively. Agreement (95% limits of agreement) for V′O2peak, RER and V′E was 0.2 (±3.7) mL·kg−1·min−1, 0.01 (±0.10) units and 2.6 (±24.0) L·min−1, respectively. No systematic or proportional bias was found except for the completed distance, which was 49 m (95% CI 16 to 82 m) longer during CPET. Conclusion Parameters of gas exchange, including V′O2peak and RER, obtained from a maximal CPET performed with the extra CLE set-up can be used interchangeably with data obtained from standard CPET, thus preventing unnecessary additional testing.http://openres.ersjournals.com/content/7/1/00825-2020.full |
| spellingShingle | Mette Engan Ida Jansrud Hammer Marianne Bekken Thomas Halvorsen Zoe Louise Fretheim-Kelly Maria Vollsæter Lars Peder Vatshelle Bovim Ola Drange Røksund Hege Clemm Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy ERJ Open Research |
| title | Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy |
| title_full | Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy |
| title_fullStr | Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy |
| title_full_unstemmed | Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy |
| title_short | Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy |
| title_sort | reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy |
| url | http://openres.ersjournals.com/content/7/1/00825-2020.full |
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