NEGATIVE PRESSURE THERAPY IN COMPLEX PROGRAM FOR TREATMENT OF PANCREATOGENIC SEPSIS

Objectives Critical analysis of the own first clinical results of the treatment in patients with pancreatogenic sepsis by inclusion of alternating negative pressure inOBJECTIVES. Critical analysis of the own first clinical results of the treatment in patients with pancreatogenic sepsis by inclusion...

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Main Authors: A. Yu. Anisimov, R. A. Yakubov, D. A. Beketov, I. V. Halturin
Format: Article
Language:Russian
Published: Sklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare Department 2017-10-01
Series:Неотложная медицинская помощь
Subjects:
Online Access:https://www.jnmp.ru/jour/article/view/386
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author A. Yu. Anisimov
R. A. Yakubov
D. A. Beketov
I. V. Halturin
author_facet A. Yu. Anisimov
R. A. Yakubov
D. A. Beketov
I. V. Halturin
author_sort A. Yu. Anisimov
collection DOAJ
description Objectives Critical analysis of the own first clinical results of the treatment in patients with pancreatogenic sepsis by inclusion of alternating negative pressure inOBJECTIVES. Critical analysis of the own first clinical results of the treatment in patients with pancreatogenic sepsis by inclusion of alternating negative pressure into the complex therapy with assessing the possibility of using NPWT as an alternative to traditional omentobursostomy.METHODS. We report the literature data and own first clinical experience in treating patients with pancreatogenic sepsis by negative variable pressure.RESULTS. The advantages of the negative variable pressure method are earlier arrest of systemic inflammatory response syndrome, continuous evacuation of exudate, effective cleansing of the wound cavity, stimulation of granulation tissue proliferation, reducing the risk of compartment syndrome, shortening of hospital stay in patients with a favorable outcome and improved quality of life in patients during their stay in hospital. The disadvantages of NPWT should include development of petechial and arrosive bleeding in 12.5%, the occurrence of intestinal fistulas in 12.5% of clinical observations.CONCLUSION. Today, it is not clear what place will NPWT take in the treatment of pancreatogenic sepsis. The data obtained in the course of literature search and analysis of our own clinical experience using the method of negative pressure therapy, indicate the need to confirm the initial clinical results in further comparative randomized controlled trials.to the complex therapy with assessing the possibility of using NPWT as an alternative to traditional omentobursostomy. Methods We report the literature data and own first clinical experience in treating patients with pancreatogenic sepsis by negative variable pressure. Results The advantages of the negative variable pressure method are earlier arrest of systemic inflammatory response syndrome, continuous evacuation of exudate, effective cleansing of the wound cavity, stimulation of granulation tissue proliferation, reducing the risk of compartment syndrome, shortening of hospital stay in patients with a favorable outcome and improved quality of life in patients during their stay in hospital. The disadvantages of NPWT should include development of petechial and arrosive bleeding in 12.5%, the occurrence of intestinal fistulas in 12.5% of clinical observations. Conclusion Today, it is not clear what place will NPWT take in the treatment of pancreatogenic sepsis. The data obtained in the course of literature search and analysis of our own clinical experience using the method of negative pressure therapy, indicate the need to confirm the initial clinical results in further comparative randomized controlled trials.
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spelling doaj.art-db0192d7fe214e3d9e0f20c2fd14b04c2023-08-02T09:12:21ZrusSklifosovsky Research Institute for Emergency Medicine, Public Healthcare Institution of Moscow Healthcare DepartmentНеотложная медицинская помощь2223-90222541-80172017-10-016322823210.23934/2223-9022-2017-6-3-228-232374NEGATIVE PRESSURE THERAPY IN COMPLEX PROGRAM FOR TREATMENT OF PANCREATOGENIC SEPSISA. Yu. Anisimov0R. A. Yakubov1D. A. Beketov2I. V. Halturin3Kazan State Medical Academy – branch of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuous Professional Education» of the Ministry of Healthcare of the Russian Federation, Kazan, Russian FederationState autonomous institution the Republic of Tatarstan “Emergency Hospital”, Naberezhnye ChelnyState autonomous institution the Republic of Tatarstan “Emergency Hospital”, Naberezhnye ChelnyState autonomous institution the Republic of Tatarstan “Emergency Hospital”, Naberezhnye ChelnyObjectives Critical analysis of the own first clinical results of the treatment in patients with pancreatogenic sepsis by inclusion of alternating negative pressure inOBJECTIVES. Critical analysis of the own first clinical results of the treatment in patients with pancreatogenic sepsis by inclusion of alternating negative pressure into the complex therapy with assessing the possibility of using NPWT as an alternative to traditional omentobursostomy.METHODS. We report the literature data and own first clinical experience in treating patients with pancreatogenic sepsis by negative variable pressure.RESULTS. The advantages of the negative variable pressure method are earlier arrest of systemic inflammatory response syndrome, continuous evacuation of exudate, effective cleansing of the wound cavity, stimulation of granulation tissue proliferation, reducing the risk of compartment syndrome, shortening of hospital stay in patients with a favorable outcome and improved quality of life in patients during their stay in hospital. The disadvantages of NPWT should include development of petechial and arrosive bleeding in 12.5%, the occurrence of intestinal fistulas in 12.5% of clinical observations.CONCLUSION. Today, it is not clear what place will NPWT take in the treatment of pancreatogenic sepsis. The data obtained in the course of literature search and analysis of our own clinical experience using the method of negative pressure therapy, indicate the need to confirm the initial clinical results in further comparative randomized controlled trials.to the complex therapy with assessing the possibility of using NPWT as an alternative to traditional omentobursostomy. Methods We report the literature data and own first clinical experience in treating patients with pancreatogenic sepsis by negative variable pressure. Results The advantages of the negative variable pressure method are earlier arrest of systemic inflammatory response syndrome, continuous evacuation of exudate, effective cleansing of the wound cavity, stimulation of granulation tissue proliferation, reducing the risk of compartment syndrome, shortening of hospital stay in patients with a favorable outcome and improved quality of life in patients during their stay in hospital. The disadvantages of NPWT should include development of petechial and arrosive bleeding in 12.5%, the occurrence of intestinal fistulas in 12.5% of clinical observations. Conclusion Today, it is not clear what place will NPWT take in the treatment of pancreatogenic sepsis. The data obtained in the course of literature search and analysis of our own clinical experience using the method of negative pressure therapy, indicate the need to confirm the initial clinical results in further comparative randomized controlled trials.https://www.jnmp.ru/jour/article/view/386infected pancreatic necrosisnegative pressure methodnpwtpancreatogenic sepsissurgical treatment
spellingShingle A. Yu. Anisimov
R. A. Yakubov
D. A. Beketov
I. V. Halturin
NEGATIVE PRESSURE THERAPY IN COMPLEX PROGRAM FOR TREATMENT OF PANCREATOGENIC SEPSIS
Неотложная медицинская помощь
infected pancreatic necrosis
negative pressure method
npwt
pancreatogenic sepsis
surgical treatment
title NEGATIVE PRESSURE THERAPY IN COMPLEX PROGRAM FOR TREATMENT OF PANCREATOGENIC SEPSIS
title_full NEGATIVE PRESSURE THERAPY IN COMPLEX PROGRAM FOR TREATMENT OF PANCREATOGENIC SEPSIS
title_fullStr NEGATIVE PRESSURE THERAPY IN COMPLEX PROGRAM FOR TREATMENT OF PANCREATOGENIC SEPSIS
title_full_unstemmed NEGATIVE PRESSURE THERAPY IN COMPLEX PROGRAM FOR TREATMENT OF PANCREATOGENIC SEPSIS
title_short NEGATIVE PRESSURE THERAPY IN COMPLEX PROGRAM FOR TREATMENT OF PANCREATOGENIC SEPSIS
title_sort negative pressure therapy in complex program for treatment of pancreatogenic sepsis
topic infected pancreatic necrosis
negative pressure method
npwt
pancreatogenic sepsis
surgical treatment
url https://www.jnmp.ru/jour/article/view/386
work_keys_str_mv AT ayuanisimov negativepressuretherapyincomplexprogramfortreatmentofpancreatogenicsepsis
AT rayakubov negativepressuretherapyincomplexprogramfortreatmentofpancreatogenicsepsis
AT dabeketov negativepressuretherapyincomplexprogramfortreatmentofpancreatogenicsepsis
AT ivhalturin negativepressuretherapyincomplexprogramfortreatmentofpancreatogenicsepsis