Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography
Background: Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tenso...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-01-01
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| Series: | NeuroImage: Clinical |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213158215000510 |
| _version_ | 1811283032595759104 |
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| author | Zhenrui Chen Yanmei Tie Olutayo Olubiyi Laura Rigolo Alireza Mehrtash Isaiah Norton Ofer Pasternak Yogesh Rathi Alexandra J. Golby Lauren J. O'Donnell |
| author_facet | Zhenrui Chen Yanmei Tie Olutayo Olubiyi Laura Rigolo Alireza Mehrtash Isaiah Norton Ofer Pasternak Yogesh Rathi Alexandra J. Golby Lauren J. O'Donnell |
| author_sort | Zhenrui Chen |
| collection | DOAJ |
| description | Background: Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tensor model. The aim of this study was to present a novel technique using a two-tensor unscented Kalman filter (UKF) algorithm to track the arcuate fasciculus (AF) in brain tumor patients with peritumoral edema.
Methods: Ten right-handed patients with left-sided brain tumors in the vicinity of language-related cortex and evidence of significant peritumoral edema were retrospectively selected for the study. All patients underwent 3-Tesla magnetic resonance imaging (MRI) including a diffusion-weighted dataset with 31 directions. Fiber tractography was performed using both single-tensor streamline and two-tensor UKF tractography. A two-regions-of-interest approach was applied to perform the delineation of the AF. Results from the two different tractography algorithms were compared visually and quantitatively.
Results: Using single-tensor streamline tractography, the AF appeared disrupted in four patients and contained few fibers in the remaining six patients. Two-tensor UKF tractography delineated an AF that traversed edematous brain areas in all patients. The volume of the AF was significantly larger on two-tensor UKF than on single-tensor streamline tractography (p < 0.01).
Conclusions: Two-tensor UKF tractography provides the ability to trace a larger volume AF than single-tensor streamline tractography in the setting of peritumoral edema in brain tumor patients. |
| first_indexed | 2024-04-13T02:03:17Z |
| format | Article |
| id | doaj.art-db02cee53001402ca9859cba957bf451 |
| institution | Directory Open Access Journal |
| issn | 2213-1582 |
| language | English |
| last_indexed | 2024-04-13T02:03:17Z |
| publishDate | 2015-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage: Clinical |
| spelling | doaj.art-db02cee53001402ca9859cba957bf4512022-12-22T03:07:33ZengElsevierNeuroImage: Clinical2213-15822015-01-017C81582210.1016/j.nicl.2015.03.009Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractographyZhenrui Chen0Yanmei Tie1Olutayo Olubiyi2Laura Rigolo3Alireza Mehrtash4Isaiah Norton5Ofer Pasternak6Yogesh Rathi7Alexandra J. Golby8Lauren J. O'Donnell9Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USABackground: Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tensor model. The aim of this study was to present a novel technique using a two-tensor unscented Kalman filter (UKF) algorithm to track the arcuate fasciculus (AF) in brain tumor patients with peritumoral edema. Methods: Ten right-handed patients with left-sided brain tumors in the vicinity of language-related cortex and evidence of significant peritumoral edema were retrospectively selected for the study. All patients underwent 3-Tesla magnetic resonance imaging (MRI) including a diffusion-weighted dataset with 31 directions. Fiber tractography was performed using both single-tensor streamline and two-tensor UKF tractography. A two-regions-of-interest approach was applied to perform the delineation of the AF. Results from the two different tractography algorithms were compared visually and quantitatively. Results: Using single-tensor streamline tractography, the AF appeared disrupted in four patients and contained few fibers in the remaining six patients. Two-tensor UKF tractography delineated an AF that traversed edematous brain areas in all patients. The volume of the AF was significantly larger on two-tensor UKF than on single-tensor streamline tractography (p < 0.01). Conclusions: Two-tensor UKF tractography provides the ability to trace a larger volume AF than single-tensor streamline tractography in the setting of peritumoral edema in brain tumor patients.http://www.sciencedirect.com/science/article/pii/S2213158215000510Arcuate fasciculusDiffusion tensor imagingPeritumoral edemaTractographyNeurosurgical planning |
| spellingShingle | Zhenrui Chen Yanmei Tie Olutayo Olubiyi Laura Rigolo Alireza Mehrtash Isaiah Norton Ofer Pasternak Yogesh Rathi Alexandra J. Golby Lauren J. O'Donnell Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography NeuroImage: Clinical Arcuate fasciculus Diffusion tensor imaging Peritumoral edema Tractography Neurosurgical planning |
| title | Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography |
| title_full | Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography |
| title_fullStr | Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography |
| title_full_unstemmed | Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography |
| title_short | Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography |
| title_sort | reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two tensor unscented kalman filter tractography |
| topic | Arcuate fasciculus Diffusion tensor imaging Peritumoral edema Tractography Neurosurgical planning |
| url | http://www.sciencedirect.com/science/article/pii/S2213158215000510 |
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