Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applications
Abstract Background Lymphedema is a progressive, noncurable condition consisting of increases in subcutaneous fat and interstitial fluid in the limbs and fibrosis during later stages. The disease most commonly affects the limbs following injury to or removal of the lymph nodes. The aim of this study...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-01-01
|
| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12957-021-02472-3 |
| _version_ | 1818974326080143360 |
|---|---|
| author | Jianfeng Xin Yuguang Sun Song Xia Kun Chang Chao Dong Zhong Liu Jian Dong Wenbin Shen |
| author_facet | Jianfeng Xin Yuguang Sun Song Xia Kun Chang Chao Dong Zhong Liu Jian Dong Wenbin Shen |
| author_sort | Jianfeng Xin |
| collection | DOAJ |
| description | Abstract Background Lymphedema is a progressive, noncurable condition consisting of increases in subcutaneous fat and interstitial fluid in the limbs and fibrosis during later stages. The disease most commonly affects the limbs following injury to or removal of the lymph nodes. The aim of this study was to investigate the therapeutic outcomes of liposuction for cancer-related lower extremity lymphedema. Methods Sixty-two patients with cancer-related lymphedema in the unilateral lower extremity were recruited for this study, and all patients underwent liposuction. The volume of hemorrhage and lipids, the operation time, and the volume changes of the affected extremity were compared by applying the t tests, and the subjective feelings of patients were compared with the chi-square tests. Results The total lipid volume was 2539 ± 1253.5 ml, and the hemorrhage volume was 828 ± 311.8 ml. For the comparison of objective indices, (1) the percent volume differences (PVDs) before surgery, intraoperatively, and at the 3-month follow-up were 5.5 ± 12.2 vs. 11.6 ± 18.4 vs. 43.2 ± 23.7, P < 0.05, respectively; (2) greater lipid volumes and higher liposuction rates were observed for female patients, as was a smaller volume of hemorrhage; (3) greater hemorrhage volumes were observed in patients with a history of recurrent erysipelas; and (4) greater lipid volumes and liposuction rates (LRs) and smaller hemorrhage volumes were observed for stage II than for stage III patients. Conclusions Liposuction is an effective therapy for cancer-related lower extremity lymphedema. Sex, stage, and recurrent erysipelas history influence the course and effect of liposuction. |
| first_indexed | 2024-12-20T15:38:16Z |
| format | Article |
| id | doaj.art-db02d8f3de9443c0b746ce32445ceb92 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-20T15:38:16Z |
| publishDate | 2022-01-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-db02d8f3de9443c0b746ce32445ceb922022-12-21T19:35:20ZengBMCWorld Journal of Surgical Oncology1477-78192022-01-012011710.1186/s12957-021-02472-3Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applicationsJianfeng Xin0Yuguang Sun1Song Xia2Kun Chang3Chao Dong4Zhong Liu5Jian Dong6Wenbin Shen7Department of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Ultrasound, Sanfine International HospitalDepartment of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Radiology, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Lymphatic Surgery, Beijing Shijitan Hospital, Capital Medical UniversityAbstract Background Lymphedema is a progressive, noncurable condition consisting of increases in subcutaneous fat and interstitial fluid in the limbs and fibrosis during later stages. The disease most commonly affects the limbs following injury to or removal of the lymph nodes. The aim of this study was to investigate the therapeutic outcomes of liposuction for cancer-related lower extremity lymphedema. Methods Sixty-two patients with cancer-related lymphedema in the unilateral lower extremity were recruited for this study, and all patients underwent liposuction. The volume of hemorrhage and lipids, the operation time, and the volume changes of the affected extremity were compared by applying the t tests, and the subjective feelings of patients were compared with the chi-square tests. Results The total lipid volume was 2539 ± 1253.5 ml, and the hemorrhage volume was 828 ± 311.8 ml. For the comparison of objective indices, (1) the percent volume differences (PVDs) before surgery, intraoperatively, and at the 3-month follow-up were 5.5 ± 12.2 vs. 11.6 ± 18.4 vs. 43.2 ± 23.7, P < 0.05, respectively; (2) greater lipid volumes and higher liposuction rates were observed for female patients, as was a smaller volume of hemorrhage; (3) greater hemorrhage volumes were observed in patients with a history of recurrent erysipelas; and (4) greater lipid volumes and liposuction rates (LRs) and smaller hemorrhage volumes were observed for stage II than for stage III patients. Conclusions Liposuction is an effective therapy for cancer-related lower extremity lymphedema. Sex, stage, and recurrent erysipelas history influence the course and effect of liposuction.https://doi.org/10.1186/s12957-021-02472-3LymphedemaLower extremityLiposuctionCancer |
| spellingShingle | Jianfeng Xin Yuguang Sun Song Xia Kun Chang Chao Dong Zhong Liu Jian Dong Wenbin Shen Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applications World Journal of Surgical Oncology Lymphedema Lower extremity Liposuction Cancer |
| title | Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applications |
| title_full | Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applications |
| title_fullStr | Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applications |
| title_full_unstemmed | Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applications |
| title_short | Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applications |
| title_sort | liposuction in cancer related lower extremity lymphedema an investigative study on clinical applications |
| topic | Lymphedema Lower extremity Liposuction Cancer |
| url | https://doi.org/10.1186/s12957-021-02472-3 |
| work_keys_str_mv | AT jianfengxin liposuctionincancerrelatedlowerextremitylymphedemaaninvestigativestudyonclinicalapplications AT yuguangsun liposuctionincancerrelatedlowerextremitylymphedemaaninvestigativestudyonclinicalapplications AT songxia liposuctionincancerrelatedlowerextremitylymphedemaaninvestigativestudyonclinicalapplications AT kunchang liposuctionincancerrelatedlowerextremitylymphedemaaninvestigativestudyonclinicalapplications AT chaodong liposuctionincancerrelatedlowerextremitylymphedemaaninvestigativestudyonclinicalapplications AT zhongliu liposuctionincancerrelatedlowerextremitylymphedemaaninvestigativestudyonclinicalapplications AT jiandong liposuctionincancerrelatedlowerextremitylymphedemaaninvestigativestudyonclinicalapplications AT wenbinshen liposuctionincancerrelatedlowerextremitylymphedemaaninvestigativestudyonclinicalapplications |