A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline
Ginseng is an international herb that has been used for thousands of years. Two species most commonly applied and investigated in the ginseng family are Asian ginseng and American ginseng. The number of randomized controlled clinical trials (RCTs) has conspicuously increased, driven by the rapid dev...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Journal of Ginseng Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1226845321000701 |
| _version_ | 1798035673535479808 |
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| author | Weijie Chen Xiuzhu Li Zhejie Chen Wei Hao Peifen Yao Meng Li Kunmeng Liu Hao Hu Shengpeng Wang Yitao Wang |
| author_facet | Weijie Chen Xiuzhu Li Zhejie Chen Wei Hao Peifen Yao Meng Li Kunmeng Liu Hao Hu Shengpeng Wang Yitao Wang |
| author_sort | Weijie Chen |
| collection | DOAJ |
| description | Ginseng is an international herb that has been used for thousands of years. Two species most commonly applied and investigated in the ginseng family are Asian ginseng and American ginseng. The number of randomized controlled clinical trials (RCTs) has conspicuously increased, driven by the rapid development of ginseng. However, the reporting of RCT items of ginseng is deficient because of different trial designs and reporting formats, which is a challenge for researchers who are looking for the data with high quality and reliability. Thus, this study focused on providing an extensive analysis of these two species and examined the quality of the RCTs, based on the Consolidated Standards of Reporting Trials (CONSORT) guideline. Ninety-one RCTs conducted from 1980 to 2019 that were related to Asian ginseng and American ginseng used singly met our inclusion criteria. We found that the reporting quality of the two species has improved during the past 40 years. Publication date and sample size were significantly associated with the reporting quality. Rigorous RCTs designed for the species of ginseng are warranted, which can shed light on product research and development of ginseng in the future. |
| first_indexed | 2024-04-11T21:01:27Z |
| format | Article |
| id | doaj.art-db0884df25ba458983b62b885baa170a |
| institution | Directory Open Access Journal |
| issn | 1226-8453 |
| language | English |
| last_indexed | 2024-04-11T21:01:27Z |
| publishDate | 2022-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Ginseng Research |
| spelling | doaj.art-db0884df25ba458983b62b885baa170a2022-12-22T04:03:30ZengElsevierJournal of Ginseng Research1226-84532022-01-014617178A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guidelineWeijie Chen0Xiuzhu Li1Zhejie Chen2Wei Hao3Peifen Yao4Meng Li5Kunmeng Liu6Hao Hu7Shengpeng Wang8Yitao Wang9State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoCorresponding author. University of Macau, Avenida da Universidade, Taipa, Macao.; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoCorresponding author. University of Macau, Avenida da Universidade, Taipa, Macao.; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, MacaoGinseng is an international herb that has been used for thousands of years. Two species most commonly applied and investigated in the ginseng family are Asian ginseng and American ginseng. The number of randomized controlled clinical trials (RCTs) has conspicuously increased, driven by the rapid development of ginseng. However, the reporting of RCT items of ginseng is deficient because of different trial designs and reporting formats, which is a challenge for researchers who are looking for the data with high quality and reliability. Thus, this study focused on providing an extensive analysis of these two species and examined the quality of the RCTs, based on the Consolidated Standards of Reporting Trials (CONSORT) guideline. Ninety-one RCTs conducted from 1980 to 2019 that were related to Asian ginseng and American ginseng used singly met our inclusion criteria. We found that the reporting quality of the two species has improved during the past 40 years. Publication date and sample size were significantly associated with the reporting quality. Rigorous RCTs designed for the species of ginseng are warranted, which can shed light on product research and development of ginseng in the future.http://www.sciencedirect.com/science/article/pii/S1226845321000701ginsengrandomized controlled clinical trialsCONSORTquality analysis |
| spellingShingle | Weijie Chen Xiuzhu Li Zhejie Chen Wei Hao Peifen Yao Meng Li Kunmeng Liu Hao Hu Shengpeng Wang Yitao Wang A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline Journal of Ginseng Research ginseng randomized controlled clinical trials CONSORT quality analysis |
| title | A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline |
| title_full | A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline |
| title_fullStr | A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline |
| title_full_unstemmed | A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline |
| title_short | A comprehensive quality analysis of randomized controlled clinical trials of Asian ginseng and American ginseng based on the CONSORT guideline |
| title_sort | comprehensive quality analysis of randomized controlled clinical trials of asian ginseng and american ginseng based on the consort guideline |
| topic | ginseng randomized controlled clinical trials CONSORT quality analysis |
| url | http://www.sciencedirect.com/science/article/pii/S1226845321000701 |
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