STAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice.

STAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice.

AIMS: Transducer and activator of transcription-3 (STAT3) plays an important role in tumor cell invasion and metastasis. The aim of the present study was to investigate the effects of STAT3 knockdown in nude mouse xenografts of pancreatic cancer cells and underlying gene expression. METHODS: A STAT3...

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Bibliographic Details
Main Authors:	Hai dong Li, Chen Huang, Ke jian Huang, Wei dong Wu, Tao Jiang, Jun Cao, Zhen zhong Feng, Zheng jun Qiu
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3185063?pdf=render

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