Joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the knee
Objective: To evaluate the clinical and functional outcomes of joint preservation surgery in high-grade giant cell tumors (GCT) around the knee joint. Methods: A retrospective review of 25 patients of high-grade GCT (Campanacci grade 2 and 3) involving proximal tibia or distal femur managed by exten...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2021-01-01
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| Series: | SICOT-J |
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| Online Access: | https://www.sicot-j.org/articles/sicotj/full_html/2021/01/sicotj210050/sicotj210050.html |
| _version_ | 1818736598404038656 |
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| author | Singh Saurabh Rai Alok Dinesh Iyer R Surana Rishabh Sharma Divyansh |
| author_facet | Singh Saurabh Rai Alok Dinesh Iyer R Surana Rishabh Sharma Divyansh |
| author_sort | Singh Saurabh |
| collection | DOAJ |
| description | Objective: To evaluate the clinical and functional outcomes of joint preservation surgery in high-grade giant cell tumors (GCT) around the knee joint. Methods: A retrospective review of 25 patients of high-grade GCT (Campanacci grade 2 and 3) involving proximal tibia or distal femur managed by extended curettage, bone grafting, and stabilization with knee spanning external fixator between 2016 and 2018 was done. The radiographic outcomes, functional outcomes (Musculoskeletal Tumor Society [MSTS] score for lower limb), and complications including donor site morbidity were evaluated. Results: The mean age of the patient population was 24.04 years with an average follow-up period of 30.24 months. Fourteen patients had involvement of distal femur, and 11 involved proximal tibia. There were 16 cases of grade 2 lesions and 9 cases of grade 3 lesions. Twenty-four out of the 25 patients had radiological consolidation of graft, while one patient had graft subsidence. Twenty-two out of 25 patients had full extension and knee flexion more than 100 degrees. The mean MSTS score was 25.2. Three patients had an MSTS score under 20. All three patients had an extension lag with a restricted range of motion. Conclusion: Joint preservation surgery, when done in line with the basic principles of tumor surgery, gives good radiographic and functional outcomes even in grade 2 and 3 giant cell tumors of bone around the knee and should be attempted before replacement surgeries. |
| first_indexed | 2024-12-18T00:39:42Z |
| format | Article |
| id | doaj.art-db0c40f775474b42ac56932b397f754f |
| institution | Directory Open Access Journal |
| issn | 2426-8887 |
| language | English |
| last_indexed | 2024-12-18T00:39:42Z |
| publishDate | 2021-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | SICOT-J |
| spelling | doaj.art-db0c40f775474b42ac56932b397f754f2022-12-21T21:26:56ZengEDP SciencesSICOT-J2426-88872021-01-0174910.1051/sicotj/2021049sicotj210050Joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the kneeSingh Saurabh0Rai Alok1https://orcid.org/0000-0002-3470-4642Dinesh Iyer R2https://orcid.org/0000-0003-4918-1415Surana Rishabh3https://orcid.org/0000-0001-6881-0446Sharma Divyansh4https://orcid.org/0000-0002-9094-4341Professor, Department of Orthopaedics, Institute of Medical Sciences, Banaras Hindu UniversityDepartment of Orthopaedics, All India Institute of Medical SciencesSenior Resident, Department of Trauma and Emergency (Orthopaedics), All India Institute of Medical SciencesSenior Resident, Department of Orthopaedics, Institute of Medical Sciences, Banaras Hindu UniversitySenior Resident, Department of Orthopaedics, All India Institute of Medical SciencesObjective: To evaluate the clinical and functional outcomes of joint preservation surgery in high-grade giant cell tumors (GCT) around the knee joint. Methods: A retrospective review of 25 patients of high-grade GCT (Campanacci grade 2 and 3) involving proximal tibia or distal femur managed by extended curettage, bone grafting, and stabilization with knee spanning external fixator between 2016 and 2018 was done. The radiographic outcomes, functional outcomes (Musculoskeletal Tumor Society [MSTS] score for lower limb), and complications including donor site morbidity were evaluated. Results: The mean age of the patient population was 24.04 years with an average follow-up period of 30.24 months. Fourteen patients had involvement of distal femur, and 11 involved proximal tibia. There were 16 cases of grade 2 lesions and 9 cases of grade 3 lesions. Twenty-four out of the 25 patients had radiological consolidation of graft, while one patient had graft subsidence. Twenty-two out of 25 patients had full extension and knee flexion more than 100 degrees. The mean MSTS score was 25.2. Three patients had an MSTS score under 20. All three patients had an extension lag with a restricted range of motion. Conclusion: Joint preservation surgery, when done in line with the basic principles of tumor surgery, gives good radiographic and functional outcomes even in grade 2 and 3 giant cell tumors of bone around the knee and should be attempted before replacement surgeries.https://www.sicot-j.org/articles/sicotj/full_html/2021/01/sicotj210050/sicotj210050.htmlgiant cell tumorcurettagejoint preservationbone graftinggct |
| spellingShingle | Singh Saurabh Rai Alok Dinesh Iyer R Surana Rishabh Sharma Divyansh Joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the knee SICOT-J giant cell tumor curettage joint preservation bone grafting gct |
| title | Joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the knee |
| title_full | Joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the knee |
| title_fullStr | Joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the knee |
| title_full_unstemmed | Joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the knee |
| title_short | Joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the knee |
| title_sort | joint preservation surgery in grade 2 and 3 giant cell tumors of bone around the knee |
| topic | giant cell tumor curettage joint preservation bone grafting gct |
| url | https://www.sicot-j.org/articles/sicotj/full_html/2021/01/sicotj210050/sicotj210050.html |
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