Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities
Baccharis trimera is a plant popularly used as a tea and to treat gastrointestinal diseases and inflammatory processes as well. The total phenolic content was determined and the antioxidant and anti-inflammatory activities of six extracts (dichloromethane, ethyl acetate, butanol, aqueous, saponin an...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-01-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/17/1/1113/ |
| _version_ | 1811228996651712512 |
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| author | Simone C. B. Gnoatto Jarbas R. de Oliveira Grace Gosmann Vanusa Manfredini Carmen Regla Vargas Lucimara N. Comunello Robson H. Amaral Gabriela Lucas da Silva Cristiane B. de Oliveira Adroaldo Lunardelli Melissa G. S. Pires |
| author_facet | Simone C. B. Gnoatto Jarbas R. de Oliveira Grace Gosmann Vanusa Manfredini Carmen Regla Vargas Lucimara N. Comunello Robson H. Amaral Gabriela Lucas da Silva Cristiane B. de Oliveira Adroaldo Lunardelli Melissa G. S. Pires |
| author_sort | Simone C. B. Gnoatto |
| collection | DOAJ |
| description | Baccharis trimera is a plant popularly used as a tea and to treat gastrointestinal diseases and inflammatory processes as well. The total phenolic content was determined and the antioxidant and anti-inflammatory activities of six extracts (dichloromethane, ethyl acetate, butanol, aqueous, saponin and phenolic) from B. trimera were evaluated. Using carrageenan-induced pleurisy as a model of acute inflammation, the phenolic extract at 15 mg/kg decreased significantly the analyzed parameters when compared to the carrageenan group ( p < 0.05), thus showing potential anti-inflammatory activity. The total phenolic content and antioxidant activity were evaluated by the Folin-Ciocalteau and DPPH methods, respectively. Phenolic and ethyl acetate extracts presented higher antioxidant activity ( p < 0.05) than ascorbic acid. The phenolic extract also showed the highest antioxidant potential in relation to the other extracts, thus suggesting that the antioxidant and anti-inflammatory activities were due to the presence of phenolic compounds. |
| first_indexed | 2024-04-12T10:06:59Z |
| format | Article |
| id | doaj.art-db0dbf27b5bb4a83848746de7c81844e |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-12T10:06:59Z |
| publishDate | 2012-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-db0dbf27b5bb4a83848746de7c81844e2022-12-22T03:37:24ZengMDPI AGMolecules1420-30492012-01-011711113112310.3390/molecules17011113Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant ActivitiesSimone C. B. GnoattoJarbas R. de OliveiraGrace GosmannVanusa ManfrediniCarmen Regla VargasLucimara N. ComunelloRobson H. AmaralGabriela Lucas da SilvaCristiane B. de OliveiraAdroaldo LunardelliMelissa G. S. PiresBaccharis trimera is a plant popularly used as a tea and to treat gastrointestinal diseases and inflammatory processes as well. The total phenolic content was determined and the antioxidant and anti-inflammatory activities of six extracts (dichloromethane, ethyl acetate, butanol, aqueous, saponin and phenolic) from B. trimera were evaluated. Using carrageenan-induced pleurisy as a model of acute inflammation, the phenolic extract at 15 mg/kg decreased significantly the analyzed parameters when compared to the carrageenan group ( p < 0.05), thus showing potential anti-inflammatory activity. The total phenolic content and antioxidant activity were evaluated by the Folin-Ciocalteau and DPPH methods, respectively. Phenolic and ethyl acetate extracts presented higher antioxidant activity ( p < 0.05) than ascorbic acid. The phenolic extract also showed the highest antioxidant potential in relation to the other extracts, thus suggesting that the antioxidant and anti-inflammatory activities were due to the presence of phenolic compounds.http://www.mdpi.com/1420-3049/17/1/1113/anti-inflammatoryantioxidantBaccharis trimeraphenolic compoundspleurisysaponinTAR |
| spellingShingle | Simone C. B. Gnoatto Jarbas R. de Oliveira Grace Gosmann Vanusa Manfredini Carmen Regla Vargas Lucimara N. Comunello Robson H. Amaral Gabriela Lucas da Silva Cristiane B. de Oliveira Adroaldo Lunardelli Melissa G. S. Pires Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities Molecules anti-inflammatory antioxidant Baccharis trimera phenolic compounds pleurisy saponin TAR |
| title | Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities |
| title_full | Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities |
| title_fullStr | Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities |
| title_full_unstemmed | Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities |
| title_short | Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities |
| title_sort | phenolic enriched extract of baccharis trimera presents anti inflammatory and antioxidant activities |
| topic | anti-inflammatory antioxidant Baccharis trimera phenolic compounds pleurisy saponin TAR |
| url | http://www.mdpi.com/1420-3049/17/1/1113/ |
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