Influence of dietary supplementation of propolis on hematology, biochemistry and lipid profile of rats fed high cholesterol diet

The objective of the present study was to monitor the hypolipidemic and hypocholesterolemic effects of propolis in rats fed high cholesterol diet. The rats (n=32) were divided into four equal groups. The rats of group 1 (control) were fed basal diet, whereas rats of group 2 were fed basal diet mixed...

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Main Author: Ibrahim Albokhadaim
Format: Article
Language:English
Published: Network for the Veterinarians of Bangladesh 2015-03-01
Series:Journal of Advanced Veterinary and Animal Research
Subjects:
Online Access:http://www.scopemed.org/fulltextpdf.php?mno=167823
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author Ibrahim Albokhadaim
author_facet Ibrahim Albokhadaim
author_sort Ibrahim Albokhadaim
collection DOAJ
description The objective of the present study was to monitor the hypolipidemic and hypocholesterolemic effects of propolis in rats fed high cholesterol diet. The rats (n=32) were divided into four equal groups. The rats of group 1 (control) were fed basal diet, whereas rats of group 2 were fed basal diet mixed with cholesterol (1%). The rats of group 3 and 4 were fed high cholesterol diet (1%) mixed with propolis powder 1 and 2%, respectively. Hematological parameters were comparable among all groups. Cholesterol, triacylglycerol and ALT activities were increased significantly in rat fed high cholesterol diet as compared to control. Inclusion of propolis in high cholesterol diets reduced these parameters in serum. Hematological and biochemical findings were supported by histopathological analysis of liver tissues. Conclusively, 1% propolis was found as safe and enough to induce beneficial hypolipidemic and hypocholesterolemic effects in serum of rats fed high cholesterol diet.
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spelling doaj.art-db0edfcb52254d13b0c53b74a99703772022-12-22T00:51:32ZengNetwork for the Veterinarians of BangladeshJournal of Advanced Veterinary and Animal Research2311-77102311-77102015-03-0121566310.5455/javar.2015.b49Influence of dietary supplementation of propolis on hematology, biochemistry and lipid profile of rats fed high cholesterol dietIbrahim Albokhadaim0Departments of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine and Animal Resources, King Faisal University, PO Box 400, Al-Hufof 31982, Saudi ArabiaThe objective of the present study was to monitor the hypolipidemic and hypocholesterolemic effects of propolis in rats fed high cholesterol diet. The rats (n=32) were divided into four equal groups. The rats of group 1 (control) were fed basal diet, whereas rats of group 2 were fed basal diet mixed with cholesterol (1%). The rats of group 3 and 4 were fed high cholesterol diet (1%) mixed with propolis powder 1 and 2%, respectively. Hematological parameters were comparable among all groups. Cholesterol, triacylglycerol and ALT activities were increased significantly in rat fed high cholesterol diet as compared to control. Inclusion of propolis in high cholesterol diets reduced these parameters in serum. Hematological and biochemical findings were supported by histopathological analysis of liver tissues. Conclusively, 1% propolis was found as safe and enough to induce beneficial hypolipidemic and hypocholesterolemic effects in serum of rats fed high cholesterol diet.http://www.scopemed.org/fulltextpdf.php?mno=167823BiochemistryBloodLipoproteinsSerumPhysiologyPropolis
spellingShingle Ibrahim Albokhadaim
Influence of dietary supplementation of propolis on hematology, biochemistry and lipid profile of rats fed high cholesterol diet
Journal of Advanced Veterinary and Animal Research
Biochemistry
Blood
Lipoproteins
Serum
Physiology
Propolis
title Influence of dietary supplementation of propolis on hematology, biochemistry and lipid profile of rats fed high cholesterol diet
title_full Influence of dietary supplementation of propolis on hematology, biochemistry and lipid profile of rats fed high cholesterol diet
title_fullStr Influence of dietary supplementation of propolis on hematology, biochemistry and lipid profile of rats fed high cholesterol diet
title_full_unstemmed Influence of dietary supplementation of propolis on hematology, biochemistry and lipid profile of rats fed high cholesterol diet
title_short Influence of dietary supplementation of propolis on hematology, biochemistry and lipid profile of rats fed high cholesterol diet
title_sort influence of dietary supplementation of propolis on hematology biochemistry and lipid profile of rats fed high cholesterol diet
topic Biochemistry
Blood
Lipoproteins
Serum
Physiology
Propolis
url http://www.scopemed.org/fulltextpdf.php?mno=167823
work_keys_str_mv AT ibrahimalbokhadaim influenceofdietarysupplementationofpropolisonhematologybiochemistryandlipidprofileofratsfedhighcholesteroldiet