Liquid Biopsy and the Translational Bridge from the TIME to the Clinic
Research and advancing understanding of the tumor immune microenvironment (TIME) is vital to optimize and direct more effective cancer immune therapy. Pre-clinical bench research is vital to better understand the genomic interplay of the TIME and immune therapy responsiveness. However, a vital key t...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/11/19/3114 |
| _version_ | 1797479960966856704 |
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| author | Paul Walker |
| author_facet | Paul Walker |
| author_sort | Paul Walker |
| collection | DOAJ |
| description | Research and advancing understanding of the tumor immune microenvironment (TIME) is vital to optimize and direct more effective cancer immune therapy. Pre-clinical bench research is vital to better understand the genomic interplay of the TIME and immune therapy responsiveness. However, a vital key to effective translational cancer research is having a bridge of translation to bring that understanding from the bench to the bedside. Without that bridge, research into the TIME will lack an efficient and effective translation into the clinic and cancer treatment decision making. As a clinical oncologist, the purpose of this commentary is to emphasize the importance of researching and improving clinical utility of the bridge, as well as the TIME research itself. |
| first_indexed | 2024-03-09T21:53:14Z |
| format | Article |
| id | doaj.art-db0fb8401a6346d8b574561ce4f9f509 |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-09T21:53:14Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-db0fb8401a6346d8b574561ce4f9f5092023-11-23T20:03:02ZengMDPI AGCells2073-44092022-10-011119311410.3390/cells11193114Liquid Biopsy and the Translational Bridge from the TIME to the ClinicPaul Walker0Rody School of Medicine at East Carolina University, Greenville, NC 27834, USAResearch and advancing understanding of the tumor immune microenvironment (TIME) is vital to optimize and direct more effective cancer immune therapy. Pre-clinical bench research is vital to better understand the genomic interplay of the TIME and immune therapy responsiveness. However, a vital key to effective translational cancer research is having a bridge of translation to bring that understanding from the bench to the bedside. Without that bridge, research into the TIME will lack an efficient and effective translation into the clinic and cancer treatment decision making. As a clinical oncologist, the purpose of this commentary is to emphasize the importance of researching and improving clinical utility of the bridge, as well as the TIME research itself.https://www.mdpi.com/2073-4409/11/19/3114liquid biopsytumor immune microenvironment |
| spellingShingle | Paul Walker Liquid Biopsy and the Translational Bridge from the TIME to the Clinic Cells liquid biopsy tumor immune microenvironment |
| title | Liquid Biopsy and the Translational Bridge from the TIME to the Clinic |
| title_full | Liquid Biopsy and the Translational Bridge from the TIME to the Clinic |
| title_fullStr | Liquid Biopsy and the Translational Bridge from the TIME to the Clinic |
| title_full_unstemmed | Liquid Biopsy and the Translational Bridge from the TIME to the Clinic |
| title_short | Liquid Biopsy and the Translational Bridge from the TIME to the Clinic |
| title_sort | liquid biopsy and the translational bridge from the time to the clinic |
| topic | liquid biopsy tumor immune microenvironment |
| url | https://www.mdpi.com/2073-4409/11/19/3114 |
| work_keys_str_mv | AT paulwalker liquidbiopsyandthetranslationalbridgefromthetimetotheclinic |