Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment
The periodontium is an appropriate target for regeneration, as it cannot restore its function following disease. Significantly, the periodontium’s limited regenerative capacity could be enhanced through the development of novel biomaterials and therapeutic approaches. Notably, the regenerative poten...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Open Exploration Publishing Inc.
2023-04-01
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| Series: | Exploration of Medicine |
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| Online Access: | https://www.explorationpub.com/Journals/em/Article/1001135 |
| _version_ | 1827954137360236544 |
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| author | Simona Santonocito Salvatore Ferlito Alessandro Polizzi Vincenzo Ronsivalle Giuseppe Reitano Antonino Lo Giudice Gaetano Isola |
| author_facet | Simona Santonocito Salvatore Ferlito Alessandro Polizzi Vincenzo Ronsivalle Giuseppe Reitano Antonino Lo Giudice Gaetano Isola |
| author_sort | Simona Santonocito |
| collection | DOAJ |
| description | The periodontium is an appropriate target for regeneration, as it cannot restore its function following disease. Significantly, the periodontium’s limited regenerative capacity could be enhanced through the development of novel biomaterials and therapeutic approaches. Notably, the regenerative potential of the periodontium depends not only on its tissue-specific architecture and function but also on its ability to reconstruct distinct tissues and tissue interfaces, implying that the development of tissue engineering techniques can offer new perspectives for the organized reconstruction of soft and hard periodontal tissues. With their biocompatible structure and one-of-a-kind stimulus-responsive property, hydrogels have been utilized as an excellent drug delivery system for the treatment of several oral diseases. Furthermore, bioceramics and three-dimensional (3D) printed scaffolds are also appropriate scaffolding materials for the regeneration of periodontal tissue, bone, and cartilage. This work aims to examine and update material-based, biologically active cues and the deployment of breakthrough bio-fabrication technologies to regenerate the numerous tissues that comprise the periodontium for clinical and scientific applications. |
| first_indexed | 2024-04-09T14:25:30Z |
| format | Article |
| id | doaj.art-db125d3b4ecd4349a72c50bab1abf314 |
| institution | Directory Open Access Journal |
| issn | 2692-3106 |
| language | English |
| last_indexed | 2024-04-09T14:25:30Z |
| publishDate | 2023-04-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Medicine |
| spelling | doaj.art-db125d3b4ecd4349a72c50bab1abf3142023-05-04T07:05:24ZengOpen Exploration Publishing Inc.Exploration of Medicine2692-31062023-04-014221523410.37349/emed.2023.00135Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatmentSimona Santonocito0https://orcid.org/0000-0003-1020-4341Salvatore Ferlito1https://orcid.org/0000-0001-7136-9698Alessandro Polizzi2https://orcid.org/0000-0001-6717-8899Vincenzo Ronsivalle3https://orcid.org/0000-0003-3059-4981Giuseppe Reitano4Antonino Lo Giudice5https://orcid.org/0000-0001-6086-2348Gaetano Isola6https://orcid.org/0000-0003-4267-6992Department of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania 95124, ItalyDepartment of Medical, Surgical Sciences and Advanced Technologies G.F. Ingrassia, Catania 95123, ItalyDepartment of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania 95124, ItalyDepartment of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania 95124, ItalyDepartment of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania 95124, ItalyDepartment of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania 95124, ItalyDepartment of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Catania 95124, ItalyThe periodontium is an appropriate target for regeneration, as it cannot restore its function following disease. Significantly, the periodontium’s limited regenerative capacity could be enhanced through the development of novel biomaterials and therapeutic approaches. Notably, the regenerative potential of the periodontium depends not only on its tissue-specific architecture and function but also on its ability to reconstruct distinct tissues and tissue interfaces, implying that the development of tissue engineering techniques can offer new perspectives for the organized reconstruction of soft and hard periodontal tissues. With their biocompatible structure and one-of-a-kind stimulus-responsive property, hydrogels have been utilized as an excellent drug delivery system for the treatment of several oral diseases. Furthermore, bioceramics and three-dimensional (3D) printed scaffolds are also appropriate scaffolding materials for the regeneration of periodontal tissue, bone, and cartilage. This work aims to examine and update material-based, biologically active cues and the deployment of breakthrough bio-fabrication technologies to regenerate the numerous tissues that comprise the periodontium for clinical and scientific applications.https://www.explorationpub.com/Journals/em/Article/1001135three-dimensional printingscaffoldsperiodontal regenerationfibrous scaffoldsperiodontal engineeringfunctional biomaterials |
| spellingShingle | Simona Santonocito Salvatore Ferlito Alessandro Polizzi Vincenzo Ronsivalle Giuseppe Reitano Antonino Lo Giudice Gaetano Isola Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment Exploration of Medicine three-dimensional printing scaffolds periodontal regeneration fibrous scaffolds periodontal engineering functional biomaterials |
| title | Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment |
| title_full | Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment |
| title_fullStr | Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment |
| title_full_unstemmed | Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment |
| title_short | Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment |
| title_sort | impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering new challenges and perspectives for disease treatment |
| topic | three-dimensional printing scaffolds periodontal regeneration fibrous scaffolds periodontal engineering functional biomaterials |
| url | https://www.explorationpub.com/Journals/em/Article/1001135 |
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