HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations

HSV-1 single-cell analysis reveals the activation of anti-viral and developmental programs in distinct sub-populations

Viral infection is usually studied at the population level by averaging over millions of cells. However, infection at the single-cell level is highly heterogeneous, with most infected cells giving rise to no or few viral progeny while some cells produce thousands. Analysis of Herpes Simplex virus 1...

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Bibliographic Details
Main Authors: Nir Drayman, Parthiv Patel, Luke Vistain, Savaş Tay
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
single-cell
RNA-sequencing
anti-viral
HSV-1
Herpes Simplex
development
Online Access:https://elifesciences.org/articles/46339

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