Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia

Nested spectral partition (NSP) method, fMRI data, machine learning and gene otology analysis show that positive and negative symptoms of schizophrenia have opposite effects on the functional organization of resting-state brains.

Bibliographic Details
Main Authors: Xinrui Wang, Zhao Chang, Rong Wang
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04637-0
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author Xinrui Wang
Zhao Chang
Rong Wang
author_facet Xinrui Wang
Zhao Chang
Rong Wang
author_sort Xinrui Wang
collection DOAJ
description Nested spectral partition (NSP) method, fMRI data, machine learning and gene otology analysis show that positive and negative symptoms of schizophrenia have opposite effects on the functional organization of resting-state brains.
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spelling doaj.art-db13ba68834f445fabd5197e008f363b2023-03-22T12:04:35ZengNature PortfolioCommunications Biology2399-36422023-03-016111210.1038/s42003-023-04637-0Opposite effects of positive and negative symptoms on resting-state brain networks in schizophreniaXinrui Wang0Zhao Chang1Rong Wang2College of Science, Xi’an University of Science and TechnologyCollege of Science, Xi’an University of Science and TechnologyCollege of Science, Xi’an University of Science and TechnologyNested spectral partition (NSP) method, fMRI data, machine learning and gene otology analysis show that positive and negative symptoms of schizophrenia have opposite effects on the functional organization of resting-state brains.https://doi.org/10.1038/s42003-023-04637-0
spellingShingle Xinrui Wang
Zhao Chang
Rong Wang
Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia
Communications Biology
title Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia
title_full Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia
title_fullStr Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia
title_full_unstemmed Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia
title_short Opposite effects of positive and negative symptoms on resting-state brain networks in schizophrenia
title_sort opposite effects of positive and negative symptoms on resting state brain networks in schizophrenia
url https://doi.org/10.1038/s42003-023-04637-0
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