PERSPECTIVE OF INNOVATION DRUG FORMULATION WITH DARUNAVIR ETHANOLAT

PERSPECTIVE OF INNOVATION DRUG FORMULATION WITH DARUNAVIR ETHANOLAT

Article shows the results of development and technological issues of darunavir ethanolate in capsule form. Soluplus was used to increase the biopharmaceutical characteristics of current drug formulation. Results of dissolution profile studies shows that intensity and release rate of API from the cap...

Full description

Bibliographic Details
Main Authors:	S. A. Zolotov, N. B. Diomina, G. F. Vasilenko, M. S. Demin
Format:	Article
Language:	Russian
Published:	LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:	Разработка и регистрация лекарственных средств
Subjects:	солюбилизация дарунавир увеличение растворимости капсулы
Online Access:	https://www.pharmjournal.ru/jour/article/view/155

Similar Items

The Effect of Solvents and Drying Temperature on the Physicochemical Properties of Darunavir and Darunavir Ethanolate Substances
by: S. A. Zolotov, et al.
Published: (2021-02-01)

PERSPECTIVE DRUG DOSAGE OF NEUTROPIC REMEDY ON THE BASIS OF EXCIPIENT FROM ROOTS OF PEGANUM HARMALA L.
by: H. I. Itzhanova, et al.
Published: (2015-09-01)

The use of nanodispersions prepared from birch bark extract for poor soluble substances solubilization.
by: V. V. Krasil’nikova, et al.
Published: (2008-10-01)

DRUG «GEOSCAPE» PRODUCED BY «B-MIN» (RUSSIA) AND ITS MONOCOMPONENTS ON THE MODEL OF EXPERIMENTAL FORMALIN ARTHRITIS IN RATS
by: M. S. Zhuravleva, et al.
Published: (2019-01-01)

Chemical and Toxicological Analysis of Antiretroviral Drugs
by: T. N. Komarov, et al.
Published: (2019-11-01)

DEVELOPMENT OF PERORAL HYPOLIPIDEMIC FORMULATION BASED ON SULFATED ARABINOGALACTAN IN THE FORM OF POTASSIUM SALT
by: Ya. A. Kostyro, et al.
Published: (2021-12-01)

ИССЛЕДОВАНИЕ ВЛИЯНИЯ УСЛОВИЙ ЭКСТРУЗИИ НА СВОЙСТВА ЭКСТРУДАТА ИЗ СМЕСИ ГРЕЧИХИ И КУКУРУЗЫ
by: Д.И. Фролов, et al.
Published: (2023-10-01)

Capsular Contraction Syndrome. Review. Part 1
by: D. I. Ivanov, et al.
Published: (2022-04-01)

DEVELOPMENT OF COMPOSITION AND TECHNOLOGY OF CAPSULES WITH OIL OF VIBURNUM
by: A. V. Brazhenko, et al.
Published: (2015-12-01)

Dependence of energy consumption in terms of 1 m 3 of concrete when using cements of different specific surface
by: A. A. Krutilin, et al.
Published: (2022-05-01)

ANALYSIS OF THE PROPOSED AIRSPACE STRUCTER OF MOSCOW ATM
by: N. I. Divak, et al.
Published: (2016-11-01)

Development of Celecoxib Granules for Manufacturing of Prolonged Release Celecoxib Capsules and Tablets
by: A. Alkhodri, et al.
Published: (2022-02-01)

Experimental substantiation of the composition of gelatin mass for obtaining capsules with essential oils
by: E. I. Molokhova, et al.
Published: (2021-12-01)

New approaches to prevention of excessive weight gain during pregnancy
by: V N Pokusaeva
Published: (2014-12-01)

Secondary cataracts after in-the-bag intraocular lens implantation: pathomorphology, pathogenesis and types. Part 1
by: S. G. Toropygin, et al.
Published: (2018-10-01)

Diseases with major salivary glands enlargement and orbits, nose and paranasal sinuses lesions in the practice of a rheumatologist
by: E. V. Sokol, et al.
Published: (2021-12-01)

Capsular Contraction Syndrome. Review. Methods of Prevention and Treatment. Part 2
by: D. I. Ivanov, et al.
Published: (2022-07-01)

ИНВЕСТИЦИИ КАК ОБЪЕКТ ИНВЕСТИЦИОННЫХ ОТНОШЕНИЙ
by: Е. Б. Бекмуханбетов
Published: (2016-02-01)

ТЕПЛОВЫЕ МЕТОДЫ ПОВЫШЕНИЯ НЕФТЕОТДАЧИ МИОЦЕНОВЫХ ЗАЛЕЖЕЙ СТАРОГРОЗНЕНСКОГО И МАЛГОБЕК-ВОЗНЕСЕНСКОГО МЕСТОРОЖДЕНИЙ
by: Д. А. Исламов
Published: (2017-07-01)

Gestational weight galns in the first trimesrter and risk of pathological birth weight deviations
by: N K Nikiforovsky, et al.
Published: (2013-12-01)

CLINICAL CASES OF LATE DIAGNOSIS OF MALIGNANT LYMPHADENOPATHY IN CHILDREN AND ADOLESCENTS
by: Григорий Михайлович Сергиенко, et al.
Published: (2022-07-01)

PERSONALIZED DATA AS A TOOL FOR MAXIMIZING THE COMPANY'S PROFIT
by: K. I. Afanaseva, et al.
Published: (2020-11-01)

Enlargement of Phimotic Capsulorhexis Using Plasma Energy: A Case Series
by: V. Kumar
Published: (2021-12-01)

Morphologic Versions of Postoperative Opacities of the Lens Capsule in Contemporary Cataract Surgery (Working Classification)
by: A. A. Fedorov, et al.
Published: (2018-10-01)

ПОРЧА ЖИВОТНЫХ ЖИРОВ. АНАЛИЗ ЖИРОВ ВАРЁНОЙ КОЛБАСЫ В УСЛОВИЯХ ОКИСЛЕНИЯ
by: Павел Юрьевич Ачаликов, et al.
Published: (2023-07-01)

INNOVATION APPROACHES TO THE DEVELOPMENT OF DRY POWDER INHALERS
by: A. N. Vorobyev, et al.
Published: (2019-01-01)

ON THE DEVELOPMENT OF A NEW STRUCTURE OF MOSCOW AREA AIRSPACE
by: N. I. Divak
Published: (2016-11-01)

Transscleral Fixation of the Dislocated IOL-Capsular Bag Complex in Contraction Capsular Syndrome
by: D. I. Ivanov, et al.
Published: (2022-04-01)

DEVELOPMENT OF A SOLID DOSAGE FORM WITH ADSORPTION ACTIVITY
by: M. V. Chirkova, et al.
Published: (2021-01-01)

«ПОСЛЕ» НЕ ЗНАЧИТ - «ВСЛЕДСТВИЕ»?ASIA-СИНДРОМ В ТЕЧЕНИЕ ГОДОВОГО НАБЛЮДЕНИЯ ПАЦИЕНТОКС ОПЕРАЦИЯМИ НА МОЛОЧНЫХ ЖЕЛЕЗАХ.ОТ ИЕГУДЫ ШЕНФЕЛЬДА - К РОМАНУ БАЕВСКОМУ
by: Валерий Геннадьевич Золотых, et al.
Published: (2021-08-01)

Algorithm for forming the structure of a selling website (by the example of developing landing page with high conversion for tourism business)
by: Ya. G. Usenko
Published: (2022-12-01)

Surgical Treatment of Patients with Dislocation of IOL — Fibrosed Capsule Bag Complexes
by: D. I. Ivanov, et al.
Published: (2022-07-01)

Features of YAG-laser treatment of posterior capsule opacification in eyes with intraocular comorbidities ext
by: O. I. Borzunov, et al.
Published: (2015-10-01)

Pharmaceutical Development of «Sedoflav» Capsules, Standardization and Validation of Flavonoids Assay Methods
by: M. A. Dzhavakhyan, et al.
Published: (2020-08-01)

Mechanisms and options of the utilization and burial of carbon dioxide in the earth interior
by: A. V. Osipov, et al.
Published: (2022-12-01)

Evaluation of the results of pansharpening multispectral images
by: Y. I. Golub
Published: (2022-06-01)

Ways to Improve the Mechanism for the Replenishment of the Profitable Part of the Local Budget of Ukraine in a Crisis Economy Пути усовершенствования механизма пополнения доходной части местных бюджетов Украины в кризисный период экономики
by: Boroh Nataliya M.
Published: (2012-06-01)

Dynamics of the ice mass in Antarctica in the time of warming
by: V. M. Kotlyakov, et al.
Published: (2017-05-01)

Technologic Considerations of Creation Dosage Form of Original Substance 3,7-diazabicyclo[3.3.1]nonane
by: G. E. Brkich, et al.
Published: (2020-11-01)

The outlooks for the adsorbent dressing based on nanostructural graphite on the bandage market of Russia
by: V. M. Vorobiyov, et al.
Published: (2010-10-01)