Computed tomography in the diagnosis of fever of unknown origin: A case report

Fever of unknown origin can be a symptom of at least 200 diseases. Positron emission tomography-computed tomography, although highly informative, may not be readily available as an imaging tool. We present a clinical case of giant cell arteritis where computed tomography played a key role in arrivin...

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Main Authors: Yuliya F. Shumskaya, Nina V. Kostikova, Dina A. Akhmedzyanova, Maria M. Suleymanova, Ekaterina V. Fominykh, Marina G. Mnatsakanyan, Roman V. Reshetnikov
Format: Article
Language:English
Published: Eco-Vector 2023-09-01
Series:Digital Diagnostics
Subjects:
Online Access:https://jdigitaldiagnostics.com/DD/article/viewFile/472068/pdf
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author Yuliya F. Shumskaya
Nina V. Kostikova
Dina A. Akhmedzyanova
Maria M. Suleymanova
Ekaterina V. Fominykh
Marina G. Mnatsakanyan
Roman V. Reshetnikov
author_facet Yuliya F. Shumskaya
Nina V. Kostikova
Dina A. Akhmedzyanova
Maria M. Suleymanova
Ekaterina V. Fominykh
Marina G. Mnatsakanyan
Roman V. Reshetnikov
author_sort Yuliya F. Shumskaya
collection DOAJ
description Fever of unknown origin can be a symptom of at least 200 diseases. Positron emission tomography-computed tomography, although highly informative, may not be readily available as an imaging tool. We present a clinical case of giant cell arteritis where computed tomography played a key role in arriving at a diagnosis. A 61-year-old woman presented to the hospital with a nocturnal fever up to 39.5°С, accompanied by chest and scapular pain, and substantial weight loss (10 kg over 3 months). Lymphoproliferative and infectious diseases were excluded. Baseline colonoscopy had revealed erosions in the colonic mucosa, leading to a preliminary diagnosis of ulcerative colitis, and subsequently, the patient was admitted to the gastroenterology department. Follow-up colonoscopy had excluded this diagnosis. Additional imaging via chest and abdominal computed tomography scan revealed wall thickening of aorta and its branches with subtle contrast enhancement. Conditions, such as tuberculous aortoarteritis and syphilitic aortitis, were excluded. The patient was diagnosed with giant cell arteritis involving brachiocephalic trunk, subclavian arteries, and celiac trunk. Prednisolone was administered with subsequent reduction in symptoms. Although computed tomography may not be regarded as the gold standard for the differential diagnosis of fever of unknown origin, this case underscores its valuable contribution in establishing a definitive diagnosis.
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spelling doaj.art-db194b783ce540e5a9cb77baa4d66f382024-02-21T15:00:46ZengEco-VectorDigital Diagnostics2712-84902712-89622023-09-014339340210.17816/DD47206876538Computed tomography in the diagnosis of fever of unknown origin: A case reportYuliya F. Shumskaya0https://orcid.org/0000-0002-8521-4045Nina V. Kostikova1https://orcid.org/0000-0003-3509-7271Dina A. Akhmedzyanova2https://orcid.org/0000-0001-7705-9754Maria M. Suleymanova3https://orcid.org/0000-0002-5776-2693Ekaterina V. Fominykh4https://orcid.org/0000-0003-3733-4381Marina G. Mnatsakanyan5https://orcid.org/0000-0001-9337-7453Roman V. Reshetnikov6https://orcid.org/0000-0002-9661-0254Research and Practical Clinical Center for Diagnostics and Telemedicine TechnologiesThe First Sechenov Moscow State Medical University (Sechenov University)Research and Practical Clinical Center for Diagnostics and Telemedicine TechnologiesThe First Sechenov Moscow State Medical University (Sechenov University)The First Sechenov Moscow State Medical University (Sechenov University)The First Sechenov Moscow State Medical University (Sechenov University)Research and Practical Clinical Center for Diagnostics and Telemedicine TechnologiesFever of unknown origin can be a symptom of at least 200 diseases. Positron emission tomography-computed tomography, although highly informative, may not be readily available as an imaging tool. We present a clinical case of giant cell arteritis where computed tomography played a key role in arriving at a diagnosis. A 61-year-old woman presented to the hospital with a nocturnal fever up to 39.5°С, accompanied by chest and scapular pain, and substantial weight loss (10 kg over 3 months). Lymphoproliferative and infectious diseases were excluded. Baseline colonoscopy had revealed erosions in the colonic mucosa, leading to a preliminary diagnosis of ulcerative colitis, and subsequently, the patient was admitted to the gastroenterology department. Follow-up colonoscopy had excluded this diagnosis. Additional imaging via chest and abdominal computed tomography scan revealed wall thickening of aorta and its branches with subtle contrast enhancement. Conditions, such as tuberculous aortoarteritis and syphilitic aortitis, were excluded. The patient was diagnosed with giant cell arteritis involving brachiocephalic trunk, subclavian arteries, and celiac trunk. Prednisolone was administered with subsequent reduction in symptoms. Although computed tomography may not be regarded as the gold standard for the differential diagnosis of fever of unknown origin, this case underscores its valuable contribution in establishing a definitive diagnosis.https://jdigitaldiagnostics.com/DD/article/viewFile/472068/pdffever of unknown origintomographyx-ray computedgiant cell arteritiscase report
spellingShingle Yuliya F. Shumskaya
Nina V. Kostikova
Dina A. Akhmedzyanova
Maria M. Suleymanova
Ekaterina V. Fominykh
Marina G. Mnatsakanyan
Roman V. Reshetnikov
Computed tomography in the diagnosis of fever of unknown origin: A case report
Digital Diagnostics
fever of unknown origin
tomography
x-ray computed
giant cell arteritis
case report
title Computed tomography in the diagnosis of fever of unknown origin: A case report
title_full Computed tomography in the diagnosis of fever of unknown origin: A case report
title_fullStr Computed tomography in the diagnosis of fever of unknown origin: A case report
title_full_unstemmed Computed tomography in the diagnosis of fever of unknown origin: A case report
title_short Computed tomography in the diagnosis of fever of unknown origin: A case report
title_sort computed tomography in the diagnosis of fever of unknown origin a case report
topic fever of unknown origin
tomography
x-ray computed
giant cell arteritis
case report
url https://jdigitaldiagnostics.com/DD/article/viewFile/472068/pdf
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