Case Series of Primaquine-Induced Haemolytic Events in Controlled Trials with G6PD Screening

Case Series of Primaquine-Induced Haemolytic Events in Controlled Trials with G6PD Screening

Primaquine for radical cure of <i>Plasmodium vivax</i> malaria poses a potentially life-threatening risk of haemolysis in G6PD-deficient patients. Herein, we review five events of acute haemolytic anaemia following the administration of primaquine in four malaria trials from Indonesia, t...

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Bibliographic Details
Main Authors: Ayleen Kosasih, Robert James, Nguyen Hoang Chau, Michelle M. Karman, Lydia Visita Panggalo, Lyndes Wini, Ngo Viet Thanh, Thomas Obadia, Ari Winasti Satyagraha, Puji Budi Setia Asih, Din Syafruddin, Walter R. J. Taylor, Ivo Mueller, Inge Sutanto, Harin Karunajeewa, Ayodhia Pitaloka Pasaribu, J. Kevin Baird
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pathogens
Subjects:
acute haemolytic anaemia
primaquine
G6PD deficiency
G6PD screening
randomized controlled trials
Online Access:https://www.mdpi.com/2076-0817/12/9/1176

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