Dextromethorphan/quinidine for the treatment of bulbar impairment in amyotrophic lateral sclerosis

Dextromethorphan/quinidine for the treatment of bulbar impairment in amyotrophic lateral sclerosis

Abstract Objective No efficacious treatments exist to improve or prolong bulbar functions of speech and swallowing in persons with amyotrophic lateral sclerosis (pALS). This study evaluated the short‐term impact of dextromethorphan/quinidine (DMQ) treatment on speech and swallowing function in pALS....

Descrizione completa

Dettagli Bibliografici
Autori principali:	Lauren Tabor Gray, Eduardo Locatelli, Terrie Vasilopoulos, James Wymer, Emily K. Plowman
Natura:	Articolo
Lingua:	English
Pubblicazione:	Wiley 2023-08-01
Serie:	Annals of Clinical and Translational Neurology
Accesso online:	https://doi.org/10.1002/acn3.51821

Documenti analoghi

Diagnostic utility of the amyotrophic lateral sclerosis Functional Rating Scale-Revised to detect pharyngeal dysphagia in individuals with amyotrophic lateral sclerosis.
di: Jennifer L Chapin, et al.
Pubblicazione: (2020-01-01)

Combined respiratory training in an individual with C9orf72 amyotrophic lateral sclerosis
di: Raele Robison, et al.
Pubblicazione: (2018-09-01)

The effect of acute administration of quinidine, dextromethorphan and combination of dextromethorphan/quinidine on pentylenetetrazole-induced clonic and tonic seizure thresholds in mice
di: Hassan Jamali, et al.
Pubblicazione: (2019-08-01)

Deuterated dextromethorphan/quinidine for agitation in Alzheimer’s disease
di: Rita Khoury
Pubblicazione: (2022-01-01)

Effects of noninvasive ventilation in amyotrophic lateral sclerosis: The complication of bulbar impairment
di: Junghyun Kim, et al.
Pubblicazione: (2020-03-01)

MRI cortical feature of bulbar impairment in patients with amyotrophic lateral sclerosis
di: Graziella Donatelli, et al.
Pubblicazione: (2019-01-01)

Two Distinct Clinical Phenotypes of Bulbar Motor Impairment in Amyotrophic Lateral Sclerosis
di: Kaila L. Stipancic, et al.
Pubblicazione: (2021-06-01)

Evaluating the safety and efficacy of dextromethorphan/quinidine in the treatment of pseudobulbar affect
di: Schoedel KA, et al.
Pubblicazione: (2014-06-01)

MANAGEMENT OF THE PSEUDOBULBAR AFFECT (PBA) IN KABUKI SYNDROME COMBINED DEXTROMETHORPHAN-FLUOXETINE TREATMENT AS AN ALTERNATIVE TO DEXTROMETHORPHAN/QUINIDINE
di: Victor Hugo Cordova, et al.
Pubblicazione: (2021-03-01)

The diagnostic pathway and prognosis in bulbar-onset amyotrophic lateral sclerosis.
di: Turner, M, et al.
Pubblicazione: (2010)

Detection of bulbar amyotrophic lateral sclerosis based on speech analysis
di: A. D. Gvozdovich, et al.
Pubblicazione: (2019-06-01)

Bulbar Onset Amyotrophic Lateral Sclerosis: A Case Report
di: Kabindra Rai, et al.
Pubblicazione: (2023-02-01)

Basilar invagination: A mimicker of bulbar-onset amyotrophic lateral sclerosis
di: Jason Seng Hong Tan, et al.
Pubblicazione: (2021-03-01)

Misdiagnosis: Hypoglossal palsy mimicking bulbar onset amyotrophic lateral sclerosis
di: Eric D. Goldstein, et al.
Pubblicazione: (2019-03-01)

Detecting bulbar amyotrophic lateral sclerosis (ALS) using automatic acoustic analysis
di: Leif E. R. Simmatis, et al.
Pubblicazione: (2024-02-01)

Predicting Early Bulbar Decline in Amyotrophic Lateral Sclerosis: A Speech Subsystem Approach
di: Panying Rong, et al.
Pubblicazione: (2015-01-01)

Agraphia in Bulbar-Onset Amyotrophic Lateral Sclerosis: Not Merely a Consequence of Dementia or Aphasia
di: Hiroo Ichikawa, et al.
Pubblicazione: (2008-01-01)

A multimodal approach to automated hierarchical assessment of bulbar involvement in amyotrophic lateral sclerosis
di: Panying Rong, et al.
Pubblicazione: (2024-05-01)

Face and content validation of the amyotrophic lateral sclerosis—Bulbar dysfunction index (ALS-BDI)
di: Yana Yunusova, et al.
Pubblicazione: (2023-01-01)

Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis
di: Hsin-Pin Lin, et al.
Pubblicazione: (2020-08-01)

Treatment of pseudobulbar affect in a mixed neurodegenerative disorder with compounded quinidine capsules and dextromethorphan cough syrup
di: Yannick Villeneuve, et al.
Pubblicazione: (2020-06-01)

Voice Assessment in Patients with Amyotrophic Lateral Sclerosis: An Exploratory Study on Associations with Bulbar and Respiratory Function
di: Pedro Santos Rocha, et al.
Pubblicazione: (2024-10-01)

Detecting Bulbar Involvement in Patients with Amyotrophic Lateral Sclerosis Based on Phonatory and Time-Frequency Features
di: Alberto Tena, et al.
Pubblicazione: (2022-02-01)

Bulbar involvement and cognitive features in amyotrophic lateral sclerosis: a retrospective study on 347 patients
di: Edoardo Nicolò Aiello, et al.
Pubblicazione: (2023-07-01)

A Clinical Scale for Rating the Severity of Bulbar Lower Motor Neuron Dysfunction in Amyotrophic Lateral Sclerosis
di: Stefano Zoccolella, et al.
Pubblicazione: (2023-07-01)

Patterns of grey and white matter changes differ between bulbar and limb onset amyotrophic lateral sclerosis
di: Robert Steinbach, et al.
Pubblicazione: (2021-01-01)

Differed brain spontaneous neural activity between limb-onset and bulbar-onset amyotrophic lateral sclerosis patients
di: Si-Jie Chen, et al.
Pubblicazione: (2025-02-01)

Validation of the Center for Neurologic Study Bulbar Function Scale–Chinese version in a population with amyotrophic lateral sclerosis
di: Shan Ye, et al.
Pubblicazione: (2024-07-01)

Bulbar-onset amyotrophic lateral sclerosis in a patient with genetically confirmed Huntington’s disease: a case study
di: Ivo Bozovic, et al.
Pubblicazione: (2024-02-01)

Comparison of Slow and Forced Vital Capacity on Ability to Evaluate Respiratory Function in Bulbar-Involved Amyotrophic Lateral Sclerosis
di: Xin Huang, et al.
Pubblicazione: (2022-06-01)

Protocol for psychometric evaluation of the Amyotrophic Lateral Sclerosis - Bulbar Dysfunction Index (ALS-BDI): a prospective longitudinal study
di: James D Berry, et al.
Pubblicazione: (2022-03-01)

Comparative study on grey matter structure MRI between amyotrophic lateral sclerosis patients with limb-onset and bulbar-onset
di: SHEN Dong-chao, et al.
Pubblicazione: (2022-07-01)

Differences in pharyngeal swallow event timing: Healthy aging, Parkinson disease, and amyotrophic lateral sclerosis
di: Pooja Gandhi, et al.
Pubblicazione: (2023-04-01)

Impaired structural motor connectome in amyotrophic lateral sclerosis.
di: Esther Verstraete, et al.
Pubblicazione: (2011-01-01)

All-in-one wearable drug efficacy assessment systems for bulbar muscle function using amyotrophic lateral sclerosis animal models
di: Beomjune Shin, et al.
Pubblicazione: (2024-08-01)

From bedside to bench - In vivo and in vitro evaluation of mechanically assisted cough treatment in a patient with bulbar Amyotrophic Lateral Sclerosis
di: Tiina Andersen, et al.
Pubblicazione: (2022-01-01)

Detection of Bulbar Involvement in Patients With Amyotrophic Lateral Sclerosis by Machine Learning Voice Analysis: Diagnostic Decision Support Development Study
di: Tena, Alberto, et al.
Pubblicazione: (2021-03-01)

Impairment in Respiratory Function Contributes to Olfactory Impairment in Amyotrophic Lateral Sclerosis
di: René Günther, et al.
Pubblicazione: (2018-02-01)

Amyotrophic lateral sclerosis.
di: Kiernan, M, et al.
Pubblicazione: (2011)

Amyotrophic lateral sclerosis
di: Leigh P Nigel, et al.
Pubblicazione: (2009-02-01)