A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval

OBJECTIVE: To evaluate the effects of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion on hemodynamic parameters, pain, sedation, and recovery score during oocyte retrieval. METHODS: Sixty-nine women were scheduled for oocyte retrieval. Target-...

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Main Authors: Demet Coskun, Berrin Gunaydin, Ayca Tas, Gozde Inan, Hulya Celebi, Kadir Kaya
Format: Article
Language:English
Published: Elsevier España 2011-01-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000500017
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author Demet Coskun
Berrin Gunaydin
Ayca Tas
Gozde Inan
Hulya Celebi
Kadir Kaya
author_facet Demet Coskun
Berrin Gunaydin
Ayca Tas
Gozde Inan
Hulya Celebi
Kadir Kaya
author_sort Demet Coskun
collection DOAJ
description OBJECTIVE: To evaluate the effects of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion on hemodynamic parameters, pain, sedation, and recovery score during oocyte retrieval. METHODS: Sixty-nine women were scheduled for oocyte retrieval. Target-controlled propofol infusion at an effectsite concentration of 1.5 μg/mL was instituted. The patients were randomly allocated to receive remifentanil at an effect-site concentration of either 1.5 (group I, n = 23), 2 (group II, n = 23) or 2.5 ng/mL (group III, n = 23). Hemodynamic variables, sedation, pain, the Aldrete recovery score, and side effects were recorded. RESULTS: Hemodynamic variables, sedation and pain scores and the number of patients with the maximum Aldrete recovery score 10 min after the procedure were comparable among the groups. The number of patients in group III with the maximum Aldrete recovery score 5 min after the procedure was significantly lower than that in groups I and II. One patient in group II and one patient in group III suffered from nausea. CONCLUSION: Similar pain-free conscious sedation conditions without significant changes in hemodynamic parameters were provided by all three protocols. However, target controlled infusion of remifentanil at 1.5 or 2 ng/mL proved superior at providing early recovery compared to 2.5 ng/mL.
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spelling doaj.art-db1d06df6b654ca28a7c3722d81285ce2022-12-22T03:37:08ZengElsevier EspañaClinics1807-59321980-53222011-01-0166581181510.1590/S1807-59322011000500017A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrievalDemet CoskunBerrin GunaydinAyca TasGozde InanHulya CelebiKadir KayaOBJECTIVE: To evaluate the effects of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion on hemodynamic parameters, pain, sedation, and recovery score during oocyte retrieval. METHODS: Sixty-nine women were scheduled for oocyte retrieval. Target-controlled propofol infusion at an effectsite concentration of 1.5 μg/mL was instituted. The patients were randomly allocated to receive remifentanil at an effect-site concentration of either 1.5 (group I, n = 23), 2 (group II, n = 23) or 2.5 ng/mL (group III, n = 23). Hemodynamic variables, sedation, pain, the Aldrete recovery score, and side effects were recorded. RESULTS: Hemodynamic variables, sedation and pain scores and the number of patients with the maximum Aldrete recovery score 10 min after the procedure were comparable among the groups. The number of patients in group III with the maximum Aldrete recovery score 5 min after the procedure was significantly lower than that in groups I and II. One patient in group II and one patient in group III suffered from nausea. CONCLUSION: Similar pain-free conscious sedation conditions without significant changes in hemodynamic parameters were provided by all three protocols. However, target controlled infusion of remifentanil at 1.5 or 2 ng/mL proved superior at providing early recovery compared to 2.5 ng/mL.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000500017Target-Controlled InfusionPropofolRemifentanilOocyte RetrievalSedation
spellingShingle Demet Coskun
Berrin Gunaydin
Ayca Tas
Gozde Inan
Hulya Celebi
Kadir Kaya
A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval
Clinics
Target-Controlled Infusion
Propofol
Remifentanil
Oocyte Retrieval
Sedation
title A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval
title_full A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval
title_fullStr A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval
title_full_unstemmed A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval
title_short A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval
title_sort comparison of three different target controlled remifentanil infusion rates during target controlled propofol infusion for oocyte retrieval
topic Target-Controlled Infusion
Propofol
Remifentanil
Oocyte Retrieval
Sedation
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000500017
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